Journal of Turkish Clinical Biochemistry

The official publication of Turkish Society of Clinical Biochemistry

Submit Your Research
Diamond OA
No APCs
First Decision
30 Days
Indexed In
TR Dizin
Original Research
August 01, 2009
JTCB. 2009 Aug 1; 7 (2) : 043-048
61 82
PDF (TÜRKÇE)

The Effect of Hyperglycemic Peak Induced by Oral Glucose Challenge Test (OGTT) on the Basal C-Reactive Protein (CRP) Level

Emin Savaş Kılavuz1, Nermin Erol2
1 Nazilli Devlet Hastanesi, Biyokimya Laboratuvarı, Nazilli, Aydın
2 Aydın İl Sağlık Müdürlüğü, Halk Sağlığı, Aydın

Abstract

Objective: The aim of this study is to examine the effect of hypeglycemic peak induced by OGTT on the basal inflammatory state by exploring the serum CRP level diffferencesMaterial and

Methods: I24 patients for suspicous of diabetes who have applied to our laboratory for OGCT were included in the study. GlucoSe levels were analyzed in zero and second hours samples for OGCT, and CRP levels were determined in zero and five hours samples. The differences observed in CRP levels were evaluated for statistical significance.

Results: Patients were categorized according to their serum glucose values; normal tolerance (n=10), impaired tolerance (n=5) and diabetic (n=9). Within the normal tolerance group, zero hour CRP levels were significantly higher than 5 hours CRP levels (p=0.047). No significant change was pertained with other groups.

Conclusion: According to the results we concluded that hyperglycemic peak induced by OGCT caused a decrease on the CRP levels, reducing the basal inflammation in normal tolerance group.

Keywords

OGTT Insulin Inflammation CRP

Citation

ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver
Kılavuz, Emin Savaş, and Nermin Erol. 2009. “The Effect of Hyperglycemic Peak Induced by Oral Glucose Challenge Test (OGTT) on the Basal C-Reactive Protein (CRP) Level”. Journal of Turkish Clinical Biochemistry 7 (2):043-048. https://turkclinbiochem.org/index.php/pub/article/view/117.
Endnote/Zotero/Mendeley (RIS) BibTeX

Publish with JTCB

Diamond Open Access

Fully Diamond OA with no APCs and no submission fees. Your research is freely available to readers worldwide from the day it publishes.

30-Day First Decision

Double-blind peer review from an active editorial team returns a first decision in about 30 days, keeping your manuscript moving.

Global Platform

Backed by the Turkish Society of Clinical Biochemistry, JTCB welcomes submissions from researchers worldwide and reaches an international laboratory audience.

Focused Laboratory Scope

Method validation, analyzer comparisons, reference intervals, quality indicators, preanalytical studies, and instructive clinical case reports.

Credible and Discoverable

All manuscripts publish in English and follow ICMJE and COPE guidelines, with Crossref DOIs and TR Dizin indexing ensuring global discoverability.

© 2026 Journal of Turkish Clinical Biochemistry. All rights reserved.