Purpose: In the recent years, the relationship between inflammation and atherosclerosis induced, which is a chronic inflammatory disease, acute coronary syndromes, including unstable angina and acute myocard infarction, has gained importance. Acute phase reactants, as...

Aim: Early risk classification after acute myocardial infarction is very important for the prediction of complications. In this study, it was aimed to find the most sensitive panel in the prediction of prognosis after acute myocardial infarction by multi-biomarker...

Objective: Acute coronary syndromes (ACS) such as unstable angina, myocardial infarction, or sudden ischemic death evolve from coronary thrombosis and as a consequence of atherosclerotic plaque disruption. “Aspirin resistance” is a poorly defined term to describe the inability...

Objective: In this study, we aimed to investigate the importance of serum pregnancy associated plasma protein A (PAPP-A) levels as an early marker before an acute myocardial infarction due to a high risk atherosclerotic plaque rupture and the relationship between PAPP-A and...

Objectives: Identifying COVID-19 patients with risk of adverse outcomes at first admission to the intensive care unit has several diagnostic challenges. The concentration of acute phase proteins synthesized by the liver increases or decreases markedly in the serum following...

Objective: Acute coronary syndrome (ACS) is a group of symptoms for acute myocardial ischemia. The RDW (red cell distribution width), recently described as a novel risk marker, has been associated with an increased risk of cardiovascular events and routinely reported as part...

Objective: Troponin I is a reliable and sensitive marker which is used to evaluate the myocardial injury. However there are different cut-off values for Troponin I due to different measurement technics. Therefore it is recommended that laboratories must define their own...

Objective: The synthesis of matrix metalloproteinase-1 (MMP-1) which is claimed to cause early mortal damage during the first moments of coronary reperfusion, is reported to be induced in-vitro by oxidized low density lipoprotein (LDL). The in- vivo changes in MMP-1, it's...

Objective: For the appropriate treatment of patients with chest-pain, measuring true CK-MB values is important for the early identification of myocardial infarction. The objective of our study was to compare the diagnostic value of the two different methods in patients with...

Objective: Automated hematology analyzer flags may provide early warning signals for hematological malignancies. This study aimed to evaluate the diagnostic performance of Sysmex XN-1000 analyzer flags and to develop a multivariable prediction model for identifying active...

Objective: Smoking is one of the most important cause of cardiovascular disease and known as a preventable risk factor. Lipoproteins especially LDL has an important role in cardiovascular disease. Normally high density lipoproteins protect LDL from oxidation; proinflammatory...

Objective: In recent years hsCRP and procalcitonin has started to be used in diagnosis and assessment of the prognosis of cardiovascular diseases. In this study we aimed to evaluate the prognostic significance of alterations in C-reactive protein (CRP) and procalcitonin...

Aim: Measurement of cardiac troponins is of great importance in the diagnosis and follow-up of acute myocardial infarction. The diagnostic specificity of myocardial infarction has increased with algorithms including serial troponin measurements. It is important that the...

Aim: In the present study, we aimed to evaluate the association between disseminated intravascular coagulation (DIC) score and mortality among adult sepsis patients in intensive care unit (ICU).

Material and Methods: In this retrospective cohort study,...

Objectives: Coronaviruses (CoV), known to exist for about 70 years, were considered animal pathogens in the 1930s. By the 1960s, they were also defined as human respiratory pathogens. Since then, CoVrelated epidemic diseases called Severe Acute Respiratory Syndrome (SARS),...

Aim: /b> In this study, we evaluated the analytical performance and diagnostic adequacy of the activity and mass methods used for the measurement of CK-MB, a laboratory marker for the diagnosis of acute myocardial infarction (AMI). In addition, the differences between CK-MB...

Background: A sedentary lifestyle is associated with cardiometabolic risk factors and obesity. This study aims to investigate the effects of regular exercise training, acute exercise, and a sedentary lifestyle on levels of miRNA-33, miRNA-335, miRNA-370, miRNA-758, which...

Aim: Leptin is a nonglycolyzed peptide, made of 146amino-acids, that is produced by ob-gene in fat tissue. Leptin in circulation shows its effects by inhibiting Neuropeptide-Y in central nervous system and shows its effects on body fat mass by decreasing appetite and...

Objective: Familial Mediterranean Fever (FMF) is an autosomal recessive disease, and it is characterized by recurrent inflammatory attacks of the serous membranes which cause periodic abdominal pain, fever and joint pain. The physiopathology of the disease seems more complex...

Objective: ST-segment elevation myocardial infarction (STEMI) is an important cause of morbidity and mortality. Platelet (PLT) activation and thrombosis have important roles in the process of atherosclerosis that is one of the most important cause of acute ischaemic...

Objective: Various inflammatory molecules that are used for diagnosis and monitoring are released into circulation when a bacterial infection is observed at host organisms. C reactive protein (CRP) is one of these various molecules, and procalcitonin (PCT) is also an acute...

Objective: Since the emergence of Coronavirus Disease 2019 (Covid-19) in December 2019, it has turned into a pandemic. Covid-19 infection; can trigger pulmonary inflammation and also cause acute lung injury. In cases with severe pneumonia, long hospital stays and high...

Objective: Ankylosing spondilitis (AS) is a chronic inflammatory disease involving primarily the skeletal system, the peripheral joints and extra-articular structures. C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) are commonly used assays for measuring...

Aim: Hepatitis C Virus (HCV) is a worldwide common virus that has an important role in the etiology of chronic hepatitis, cirrhosis and hepatocellular carcinoma (HCC). HCV is a disease that causes different pathologies ranging from asymptomatic carriage to acute hepatitis,...