In research studies performed to enlighten the diagnosis and pathogenesis of various diseases and to investigate possible treatment strategies, experimental animal models provide many advantages to the investigators. Diabetes Mellitus is a chronic metabolic disease which lasts for whole life,...

Objective: Sialic acid, known as a risk factor for coronary heart disease is also elevated in serum after myocardial infarction. Because acute myocardial infarction generally develops on the basis of atherosclerotic heart disease, the effect of experimental myocardial...

Sickle cell disease is a blood disorder that affects erythrocytes one of the most common single gene disorders in the world and the incidence is high in Turkey. Mutation in the beta globin gene leads to the formation of sickle hemoglobin tetramers. These tetramers polymerize and damage the...

Neutrophil gelatinase-associated lipocalin (NGAL), is a small, robust protein expressed by neutrophils and various epithelia, including the renal proximal tubules. While initially proposed as a marker for infections and certain adenocarcinomas, it is now apparent that its early and dramatic rise...

Background: The purpose of this study was to investigate the superiority of serum cystatin C levels over serum urea and creatinine in evaluating kidney functions in intensive care unit patients.

Material and Methods: 65 patients in intensive care unit...

Objective: In this study, we aimed to show whether conditions which cause positive results in 50 gr gestational diabetes screening test also increase the levels of inflammatory markers in pregnant women.

Materials and Methods: Fasting fibrinogen and...

Objective: In this study, salivary alpha-amylase activity was measured to elaborate on sympathetic nervous system activity in athletes.

Materials and Methods: Six male subjects between 18-21 years of age participated in two 4-hour long trials (exercise...

Sepsis is defined as systhemic response against infections and frequently caused by gram negative bacteria. It is proposed that the blood levels of acute phase reactants such as Lipopolisaccharide Binding Protein (LBP), C-reactive protein (CRP), mediators of septic cells such as Tumor Necrosis...

Objective: Familial Mediterranean Fever (FMF) is an autosomal recessive disease, and it is characterized by recurrent inflammatory attacks of the serous membranes which cause periodic abdominal pain, fever and joint pain. The physiopathology of the disease seems more complex...

Objective: ST-segment elevation myocardial infarction (STEMI) is an important cause of morbidity and mortality. Platelet (PLT) activation and thrombosis have important roles in the process of atherosclerosis that is one of the most important cause of acute ischaemic...

Objective: Various inflammatory molecules that are used for diagnosis and monitoring are released into circulation when a bacterial infection is observed at host organisms. C reactive protein (CRP) is one of these various molecules, and procalcitonin (PCT) is also an acute...

Objective: Since the emergence of Coronavirus Disease 2019 (Covid-19) in December 2019, it has turned into a pandemic. Covid-19 infection; can trigger pulmonary inflammation and also cause acute lung injury. In cases with severe pneumonia, long hospital stays and high...