Objective: Thyroid function, influenced by age and sex, provides important epidemiological information when evaluated at the population level. This study aimed to investigate age- and sex-related differences in thyroid-stimulating hormone (TSH), free triiodothyronine (fT3),...

The purpose of this study was to measure serum adenosine deaminase (ADA) and ceruloplasmin (CP) activities in the second trimester pregnants who had high age and down syndrome (DS) risk as compared with non-pregnants. This preliminary study was made with 280 pregnants who gave blood samples for...

Aim: This study aimed to evaluate the distribution and trends of ethanol analysis results according to age, gender, and ethanol concentration levels over a four-year period.

Materials and Methods: In this retrospective study, a total of 11,684 ethanol...

Objective: Cardiovascular diseases (CVD) are the leading causes of death worldwide. After understanding the importance of inflammation in the pathogenesis, CRP usage has been increased for the determination of cardiovascular risk. As an inflammation marker, the relationship...

Objectives: Despite various studies on the effect of thyroid status on insulin sensitivity in recent years, there are conflicting data. Thyroid dysfunction leads to changes in glucose and lipid metabolism, which is an important risk factor for cardiovascular diseases. For this...

Aim: The present study aimed to determine the reference range values for four lipid parameters associated with chronic diseases that were routinely examined in our laboratory in elderly individuals aged ≥65 years.

Materials and Methods: We determined...

Aim: Polycystic ovarian syndrome (PCOS) is a multifactorial disorder with different phenotypic characteristics, the most frequent endocrine disorder in women, and the leading cause of anovulatory infertility. Kisspeptin is recognized to have a crucial function in regulating...

Aim: It was aimed to determine predictive markers for the need for intensive care unit (ICU) hospitalization in patients with coronavirus infection.

Material and Methods: This study was performed retrospectively from data of patients hospitalized with...

Aim: During iron deficiency anemia (IDA), increased oxidative stress is accompanied by reduction in antioxidant defense systems and increased lipid peroxidation. We aimed to assess oxidative balance and Deoxyribonucleic Acid (DNA) damage in reproductive-aged women with...

Objectives: There are not enough studies based on laboratory results regarding the prevalence of Substance Use Disorders in our country, The purpose of this retrospective study is; to determine the distribution of the substances used by dependent individuals with treatment...

Objective: Glomerular filtration rate is one of the best indicators of renal function. It is usually determined indirectly by calculating renal clearance of endogenous filtration markers creatinine or urea. In addition, different formulas have been developed for determining...

Aim: Autism Spectrum Disorder (ASD) etiopathogenesis remains unclear, and it is a progressively prevalent condition. It has been demonstrated that vitamin D plays an important role not only in bone metabolism but also in brain maturation. Vitamin D and its metabolizing enzymes...

Aim: Regarding coronavirus disease (COVID-19), despite antibody measurement alone providing insufficient data, studies evaluating immune responses to vaccination or disease have focused on humoral immunity. Uncoupled humoral and cellular responses may be present after...

Aim: Although, urine culture requests to diagnose urinary tract infection (UTI) are very common, about 70-80% of urine samples received in the laboratory are found to be negative. This means increased laboratory workload and cost. Urinary leukocyte esterase and nitrite are...

Objective: Low molecular weight proteins serum Cystatin C (sSC), β-2 Microglobulin (sβMg), Retinol Binding Protein (sRBP) have been proposed for estimation of Glomerular Filtration Rate (GFR). This study is designed to see how these proteins change with alterations of GFR in...

Purpose: The maturation of hemostatic system continues from fetal life to adult. Determination of agedependent reference ranges for coagulation is therefore very important to evaluate correctly the hemostasis. The study aimed to establish age-dependent reference range for...

Aim: Smoking is accepted as a risk factor for primary chronic diseases such as cardiovascular diseases and respiratory system diseases and for cancer development. The aim of this study was to indicate the increase in inflammation in smokers by using high-sensitivity...

Objective: Hyperphosphatemia and high calcium X phosphate product are significant and common risk factors of cardiovascular disease in patients with chronic kidney disease. However, the relationship is not clear between increased risk and hyperphosphatemia and elevated calcium...

Objective: Elevated ischemia modified albumin (IMA) and C-reactive protein (CRP) levels have been reported as a result of ischemia, which is due to atherosclerosis and increased inflammatory processes. We measured serum CRP levels and ESR to determine inflammatory status of...

Objective: Pre-eclampsia is a pregnancy specific form of hypertension and a multisystem disorder of maternal and placental origin. Pregnancy associated plasma protein-A (PAPP-A) is a insulin like growth factor binding protein 4- degrading metalloproteinase. The aim of this...

Aim: Idiopathic hyperandrogenemia is defined as the disease in women with signs of hirsutism and increased serum androgen levels, a normal menstrual cycle, and normal ovarian morphology. In this study, it was aimed to examine the association of Bisphenol A and mono-ethylhexyl...

Aim: The aim of this study is to investigate the possible effects of chronic smoking on serum vitamin D and some inflammation markers.

Materials and Methods: The smoking history of a total of 110 volunteer adults, 76 females and 34 males, for whom 25...

Objective: There is an increase in platelet activation in diabetics and patients with diabetic complications. Labile hemoglobin A1c (LHbA1c), an early glycation product, can turn into other glucose metabolites which can be responsible for many kinds of pathologies observed...

Objective: The discovery of vitamin D receptors and vitamin D activating enzymes in several cells other than those involved in bone and mineral metabolism brought the non-classical effects of vitamin D into focus. It was reported that diabetic patients have significantly...

Objective: In this study we aimed to calculate the reference intervals of carbohydrate antigen 15-3 (CA15-3), carbohydrate antigen 19-9 (CA19-9), carbohydrate antigen 125 (CA125) and carsinoembriyogenic antigen (CEA).

Materials and Methods: 325 healthy...