Purpose: Rheumatoid arthritis (RA) is a chronic, progressive, autoimmune disease characterized by synovial inflammation, cartilage damage and bone erosion. Ischemia modified albumin (IMA) is a potential marker that can be used to assess atherosclerosis-related myocardial...

Background: Bromcresol green (BCG) and Bromcresol Purple (BCP) which are dye-binding based methods are widely used in serum albumin analysis in clinical laboratories for many years. It was suggested that discrepancies exist between these methods and these discrepancies are...

Objective: This study aimed to evaluate the agreement between albumin measurements obtained via capillary zone electrophoresis (CZE) and bromocresol green (BCG) methods and to determine their interchangeability in clinical practice. Additionally, it explored how these results...

Purpose: We aimed to investigate pentraxin 3 and placental protein 13 levels related to the pathogenesis of the disease, as well as albumin, lactate dehydrogenase, uric acid and platelet count values, which are frequently requested laboratory tests, in second and third...

Objective: The increase in serum procalcitonin (PCT) levels is a marker of severe systemic inflammation due to bacterial infection and renal excretion plays an important role in its elimination. The aim of this retrospective study is to investigate the relationship between...

Aim: Smoking is accepted as a risk factor for primary chronic diseases such as cardiovascular diseases and respiratory system diseases and for cancer development. The aim of this study was to indicate the increase in inflammation in smokers by using high-sensitivity...

Background: It is thought that using a spot urine is more appropriate for microalbuminuria screening than 24 hours timed urine specimens due to collection and standardization difficulties. In this study, we examined the availability of spot urine as a screening test for the...

Aim: Chronic kidney disease (CKD) is highly prevalent, with increasing numbers of patients affected by the disease world-wide (1). Anemia is a common complica- tion that contributes to the burden of disease associated with CK D, and it impacts negatively on cardiovascular...

Objective: Glomerular Filtration Rate (GFR) is the best indicator for the reflecting of kidney function in health and disease. In this study we compared -Glomerular Filtration Rate (GFR) calculation formulas – 4 variables Modification of Renal Disease (MDRD) formula with the 6...

Objectives: Identifying COVID-19 patients with risk of adverse outcomes at first admission to the intensive care unit has several diagnostic challenges. The concentration of acute phase proteins synthesized by the liver increases or decreases markedly in the serum following...

Background: The evaluation of pre-analytical, analytical and post-analytical phases is very important to obtain accurate, price and comparable results. Quality indicators are generally used to evaluate these processes. The present study aimed to evaluate the analytical phase...

Aim: Rheumatoid arthritis (RA) is an autoimmune disease and its etiology hasnt been fully elucidated. However, excessive amounts of reactive oxygen derivatives have been detected in the synovial fluids of patients with RA. Therefore, systemic inflammation and oxidative...

Objective: Elevated ischemia modified albumin (IMA) and C-reactive protein (CRP) levels have been reported as a result of ischemia, which is due to atherosclerosis and increased inflammatory processes. We measured serum CRP levels and ESR to determine inflammatory status of...

Objective: In this study, we aimed to evaluate the possible effects of leptin and oxidative stress on the pathogenesis of type 1 and type 2 diabetes mellitus.

Material and Methods: Subjects were assigned to four groups: type 1 diabetes group (n=20),...

Aim: In the present study, we aimed to evaluate the association between disseminated intravascular coagulation (DIC) score and mortality among adult sepsis patients in intensive care unit (ICU).

Material and Methods: In this retrospective cohort study,...

Aim: The Intra-laboratory Turnaround Time (IR-TAT) serves as a significant measure of overall laboratory efficacy. This study sought to augment laboratory operational productivity and diminish IR-TAT by instating a Total Laboratory Automation (TLA) system, executing stat...

Objective: Acryla mide is formed during cooking, frying and burning at high temperatures, of many commonly consumed foods. After determining the adverse effects of acrylamide on health, increased the research numbers on this topic. The aim of this study was to investigate...

Aim: In this study, we aimed to evaluate the analytical process performance of clinical biochemistry parameters by six sigma method and to make the necessary arrangements according to the obtained results in our laboratory.

Material and Methods: In...

Objective: Since the emergence of Coronavirus Disease 2019 (Covid-19) in December 2019, it has turned into a pandemic. Covid-19 infection; can trigger pulmonary inflammation and also cause acute lung injury. In cases with severe pneumonia, long hospital stays and high...

Objective: In quantitative analysis of serum proteins turbidimetric and nephelometric methods are the most common. Aim of this study was to compare the nephelometric method with the turbidimetric method for serum and urine samples in our clinical laboratory and to analyse...

Objective: In this study in which the purpose was to investigate the effect of hemodialysis treatment on cardiac markers and trace elements, serum copper, zinc, homocysteine and lipoprotein (a) levels and ceruloplasmin oxidase and adenosine deaminase activities and compared...