The official publication of Turkish Society of Clinical Biochemistry
Objective: Defibrotide, a polydeoxyribonucleotide, has been found to modulate endothelial cell function and to have an antithrombotic effect on arteries, veins and capillaries. A significant amonut of evidence has been found about the protective role of defibrotide in...
Objective: Nicotine is an important component of cigarette smoke. Nicotine administration may result in oxidative stress by inducing the generation of reactive oxygen species in the periphery and central nervous system. Numerous epidemiological studies have demonstrated an...
Objective: The oxidative stress and renal vasoconstriction are considered to have an effect on the pathophysiology of contrast induced nephropathy. In this study, we aimed to evaluate the effects of contrast agents on serum creatinine, total antioxidant capacity and estimated...
Purpose: To investigate the effects of melatonin on serum paraoxonase and lactonase activities in isoproterenol-induced myocardial infarction.
Materials and Methods: Rats were divided into four groups as control, melatonin, ISO and ISO+melatonin....
Objective: The aim of this study was to evaluate the effects of nicotine on myocardium of newborn rats whose mothers received nicotine during gestation and lactation, by using biochemical and pathological parameters and to evaluate the role of antioxidant enzymes, free oxygen...
Objective: It has been reported that liver oxidative stress increases in streptozotocin induced experimental diabetes. The aim of this study is to investigate the effects of L-carnitine possessing antioxidant activity on liver protein oxidation seen in diabetes.
...Purpose: Obstructive jaundice leads to hepatic injury and fibrosis. Icterus causes immunologic depression resulting in bacterial translocation. In this study, we aimed to investigate the effects of vitamin E and L-arginine supplementation on glutathione systems and bacterial...
Aim: The oxidative stress which is caused by free radicals can play role in emerging and/or progressing many diseases. Hyperthyroidism can induce a lot of changes dealing with the systems of nitric oxide (NO) and antioxidant systems of several tissues in increasing the...
Objective: In this study, we aimed to evaluate the possible effects of leptin and oxidative stress on the pathogenesis of type 1 and type 2 diabetes mellitus.
Material and Methods: Subjects were assigned to four groups: type 1 diabetes group (n=20),...
Fully Diamond OA with no APCs and no submission fees. Your research is freely available to readers worldwide from the day it publishes.
Double-blind peer review from an active editorial team returns a first decision in about 30 days, keeping your manuscript moving.
Backed by the Turkish Society of Clinical Biochemistry, JTCB welcomes submissions from researchers worldwide and reaches an international laboratory audience.
Method validation, analyzer comparisons, reference intervals, quality indicators, preanalytical studies, and instructive clinical case reports.
All manuscripts publish in English and follow ICMJE and COPE guidelines, with Crossref DOIs and TR Dizin indexing ensuring global discoverability.