The official publication of Turkish Society of Clinical Biochemistry
Objective: Intact parathyroid hormone is used for diagnostic follow up in chronic kidney disease mineral bone disorder. Studies have shown that there was considerable bias between methods intact parathyroid hormone assays. This study has investigated the variation between...
Objective: The aim of this study, was to determine whether the Troponin I and CK-MB test results obtained from our laboratory meet the acceptable quality standards.
Material and Methods: Total %CV of troponin I and CK-MB was obtained from internal...
Aim: Six Sigma is a quality management tool that helps continuously monitor and improve the performance of the tests in the clinical laboratory. The quality goal index (QGI) ratio represents the state of meeting the respective quality targets of both bias and precision. The...
Purpose: The measurement uncertainty is a quantitative indicator of the quality of the test result obtained and indicates how the test results represent the actual value. For this reason, we aimed to calculate the measurement uncertainty for the 25-hydroxyvitamin D3 assay,...
Aim: Sigmametric methodology is used as a quality management tool that predicts variables can be controlled and targets zero error.In this study, sigmametrics were calculated for some fertility function tests to pick the suitable quality control tools and approach for...
Aim: Method evaluation studies should be carried out for every new method planned to be used in laboratories. The aim of this study is to determine the analytical performance of the immunoassay method used for determining of plasma 25-hydroxy vitamin D levels and also to...
Aim: In this study, we aimed to evaluate the analytical process performance of clinical biochemistry parameters by six sigma method and to make the necessary arrangements according to the obtained results in our laboratory.
Material and Methods: In...
Aim: Six sigma is a quality management tool used to evaluate analytical process performance. We evaluated the performance of biochemical and immunological tests on a Roche Cobas 8000 device in our laboratory using sigma metrics.
Materials and Methods:...
Objective: We aimed to investigate the possible differences between the analytical assay and estimation with Friedewald formula of LDL cholesterol in patients divided into subgroups according to direct LDL cholesterol, triglyceride, total cholesterol levels,...
Background: The evaluation of pre-analytical, analytical and post-analytical phases is very important to obtain accurate, price and comparable results. Quality indicators are generally used to evaluate these processes. The present study aimed to evaluate the analytical phase...
Objective: The cardiac troponins are sensitive and specific biochemical markers of myocardial damage. It has been suggested that hemolysis causes interference in the immunometric cardiac troponin assay. The current study aimed to determine the significance of hemolysis as an...
Purpose: The measurement of serum ferritin is used as a reliable and noninvasive method for the monitoring of iron stores. There are many different methods for the ferritin measurement. However, the immunoturbidimetric method that having the less cost and possibility of the...
Objective: This study aimed to evaluate the agreement between albumin measurements obtained via capillary zone electrophoresis (CZE) and bromocresol green (BCG) methods and to determine their interchangeability in clinical practice. Additionally, it explored how these results...
Aim: Panic value refers to a laboratory test result that is life-threatening and requires immediate corrective action by the physician. Although there is no recommendation to re-run the panic-valued test, some laboratory specialists report the result after repeating the test....
Objective: The use of different types of analyzers and samples lead to obtaining different test results. This study aimed to investigate whether the test results yielded by conventional blood gas analyzer (cBGA) are considered interchangeable with those produced by...
Objective: The aim of this study is to investigate the compatibility of bicarbonate (HCO3-) levels measured by blood gas meter in serum autoanalyser.
Materials and Methods: In the study, serum bicarbonate and blood gas bicarbonate levels of 186...
Aim: Measurement uncertainty provides information about the limits at which the measured value may vary as a result of random effects in a biochemical measurement. It is a quantitative indicator of the quality of the result obtained and allows us to estimate the extent to...
Objective: Test analyses in laboratories must leave neither clinician nor patient in doubt. Measurement uncertainty must therefore be studied for all tests in laboratories. The aim of this study was to calculate the measurement uncertainty of the hormone...
Objective: To compare the analytical performance of 2 immunoturbidimetric C-reactive protein (CRP) reagents using the same automated analyzer and to evaluate whether an alternative reagent provides clinically acceptable results.
Methods: This...
Objective: Analytical reliability of clinical laboratories may be obtained by internal quality control, external quality control by analyzing the data with statistical methods. In Six Sigma Methodology, which is one of these methods, the analytical performance of the tests...
Aim: This study aimed to evaluate the performance characteristics of preliminary coagulation tests on the Sysmex CS-5100 coagulation autoanalyzer and compare it with the ACL Top 700 autoanalyzer. Both analyzers were assessed for their ability to measure prothrombin time (PT),...
Aim: Cross-reactivity in immunological techniques varies and the frequency depends on the population of the study, technique for detecting the reaction and researchers method. In this study our aim was to evaluate the cross-reactivity in thyroid function tests.
...Aim: Six Sigma methodology used in clinical laboratories is a quality management tool based on statistical calculations, focusing on process variables and providing information about process performance. In this study, we aimed to evaluate the analytical process performances...
Aim: In this study, we compared 3 different clot-activator gel tubes to a glass reference tube and evaluated the effect of storage time on 30 different biochemical analytes.
Material and Methods: Blood samples were collected in 4 types of tubes: an...
Objective: If a new analyzer in the laboratories is considered to be used, method comparison should be done. Two analyzers should be compared in order to evaluate accuracy of the new analyzer. In our study, we aimed to compare the performance of new coagulation analyzer with...
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