Evin Kocatürk, Alparslan Birdane, Arif Alper Cevik, Ertugrul Colak, Ahmet Musmul, Omer Colak
Aim: Early risk classification after acute myocardial infarction is very important for the prediction of
complications. In this study, it was aimed to find the most sensitive panel in the prediction of prognosis
after acute myocardial infarction by multi-biomarker...
Journal of Turkish Clinical Biochemistry
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2022-12-01
Merve Zeytinli Akşit, Yasemin Delen Akçay, Çiğdem Gözde Aslan, Yusuf Ali Altuncı, Murat Ersel, Alper Bozdoğan
Aim: We aimed to reveal the potential roles of periostin, hypoxia-inducible factor-1α (HIF-1α), and phospholipase A2 (PLA2) in inflammation, hypoxia, and tissue damage in patients with coronavirus disease 2019 (COVID-19) and to investigate whether they are useful potential...
Journal of Turkish Clinical Biochemistry
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2025-12-01
Fatma Ucar, Seyda Ozdemir, Gulfer Ozturk, Ali Yalcindag
Objectives: The carbohydrate antigen 19-9 assay is a widely used biomarker as a complement to other
tests in the detection and follow-up of pancreatic, bile duct and colon cancer in high-risk individuals.
The CA 19-9 assays often give different results with different...
Journal of Turkish Clinical Biochemistry
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2022-08-01
Ayça Tuzcu, Kenan Yörük, Gülnur Taşçı Bozbaş, Aslıhan Büyüköztürk, Mustafa Yılmaz
Objective: To assess iodine status in adults with euthyroid in Aydın province using spot urinary iodine concentration (UIC) and the urinary iodine-to-creatinine (I/Cr) ratio and to evaluate the relationship between serum thyroglobulin (Tg) and iodine status.
...
Journal of Turkish Clinical Biochemistry
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2026-08-25
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DOI: 10.65717/jtcb.2026.26037
Raziye Topkafa, Abdullah Sivrikaya, Duygu Eryavuz Onmaz, Gulsum Abuşoğlu, Muhammet Limon, Sema Yılmaz, Ali Ünlü
Aim: Homocitrulline (Hcit) is a modified amino acid originated by carbamylation of lysine residues and
it is considered a potential biomarker in inflammatory diseases. Behçet's disease (BD) is an
autoinflammatory disease, the diagnosis of the disease is based on clinical...
Journal of Turkish Clinical Biochemistry
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2022-08-01
Giray Bozkaya, Sibel Bilgili
Introduction: The disease caused by SARS-CoV-2, which the World Health Organization has
considered as a pandemic, was named COVID-19 and has since spread worldwide. The COVID-19
pandemic has drastically changed the way we live and work. During events like COVID-19, it is...
Journal of Turkish Clinical Biochemistry
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2022-04-01
Inanc Karakoyun, Fatma Demet Arslan
Aim: Pancreatic cancer (PC) is a disease with complex and poorly understood etiology. One of the
common risk factors of PC is diabetes mellitus (DM). Increased carbohydrate antigen (CA) 19-9 levels
can be used as a biomarker in diagnosis of PC. However, CA 19-9 levels have...
Journal of Turkish Clinical Biochemistry
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2020-12-01
Özben Özden Işıklar
Galectin-3 is a multifunctional protein that plays a critical role in inflammation, apoptosis, and fibrosis. It is considered a biomarker and therapeutic target in cardiovascular and neurodegenerative diseases, as well as pulmonary, hepatic, and renal fibrosis. Additionally, it is associated with...
Journal of Turkish Clinical Biochemistry
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2025-04-01
Muzaffer Katar, Merve Çatak
Objective: Obesity represents a significant global health concern characterized by substantial metabolic abnormalities and a heightened risk of developing type 2 diabetes mellitus (T2DM). Novel peptides including irisin, adropin, and preptin have been shown to play important...
Journal of Turkish Clinical Biochemistry
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2026-08-25
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DOI: 10.65717/jtcb.2026.26021
Emel Altekin, Yasin Kenesarı
Neutrophil gelatinase-associated lipocalin (NGAL), is a small, robust protein expressed by neutrophils and various epithelia, including the renal proximal tubules. While initially proposed as a marker for infections and certain adenocarcinomas, it is now apparent that its early and dramatic rise...
Journal of Turkish Clinical Biochemistry
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2013-04-01
Tevfik Noyan
D-dimer antigen is a fibrin degradation product that is formed by the sequential action of three different enzymes on cross-linked fibrin. As such, increased levels of plasma D-dimer should be reliable indicator of thrombus formation. The D-dimer antigen is a specific marker of fibrin clot...
Journal of Turkish Clinical Biochemistry
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2012-04-01
Arzu Ateş, Ayça Tuzcu, Aslıhan Büyüköztürk
Purpose: Although most studies showed that the increase of cardiac biomarkers due to myocardial injury during coronavirus disease (COVID-19) is a strong predictor of adverse clinical events, few studies compared other causes of myocardial injury and COVID-19. In our study,...
Journal of Turkish Clinical Biochemistry
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2025-08-01
Sevda Ünallı Özmen, Yeşim Özarda
Amyotrophic lateral sclerosis (ALS) is a fatal disorder of motor neuron degeneration with unclear etiology
and no effective treatment to date. The cause of the most cases of ALS remains unknown. Research
in ALS has been stimulated by a series of genetic and molecular pathology discoveries. ALS...
Journal of Turkish Clinical Biochemistry
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2014-12-01
Hamza Malik Okuyan, Serdar Doğan, Tayibe Bal, Mehmet Çabalak
Aim: The COVID outbreak is a serious health problem affecting socio-economic life and healthcare systems worldwide. Although the role of Semaphorins in some diseases is relatively known, the association of these molecules with the pathogenesis of COVID-19 remains unclear....
Journal of Turkish Clinical Biochemistry
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2023-08-01
Meltem Demir
Anti-Mullerian hormone (AMH), also called Mullerian inhibiting substance (MIS), belongs to the transforming growthfactor- Β (TGF- Β) superfamily. In women, AMH is produced by granulosa cells beginning from 36 weeks of gestation until menapause, with the highest expression being in small antral...
Journal of Turkish Clinical Biochemistry
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2013-08-01