Özben Özden Işıklar, Güneş Başol, Burcu Barutçuoğlu, Erkin Bozdemir, Ceyda Kabaroğlu, Zuhal Parıldar, Işıl Mutaf, Dilek Özmen
Objective: After proving that chronic low grade inflammation is an important component of atherosclerotic process, C-reactive protein (CRP) has been started to be used for atherosclerotic vascular disease risk determination together with the other risk factors. In practice, to...
Journal of Turkish Clinical Biochemistry
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2007-04-01
Rabia Nur Kocabaş, A. Erkin Bozdemir, Güneş Başol, Burcu Barutçuoğlu, Zuhal Parıldar, Ceyda Kabaroğlu, Oya Bayındır
Objective: Cardiovascular diseases (CVD) are the leading causes of death worldwide. After understanding the importance of inflammation in the pathogenesis, CRP usage has been increased for the determination of cardiovascular risk. As an inflammation marker, the relationship...
Journal of Turkish Clinical Biochemistry
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2007-08-01
Hüseyin Kurku, İbrahim Solak, Yavuz Turgut Gederet, Mehmet Ali Eryilmaz
Aim: Smoking is accepted as a risk factor for primary chronic diseases such as cardiovascular diseases
and respiratory system diseases and for cancer development. The aim of this study was to indicate the
increase in inflammation in smokers by using high-sensitivity...
Journal of Turkish Clinical Biochemistry
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2021-04-01
Sibel Bilgili, Gizem Yalçın, Giray Bozkaya, Nuriye Uzuncan, Arife Erdoğan
Purpose: Nitric oxide(NO) is one of the important substances that are synthesized to keep the blood
vessels dilated enough to provide adequate flow and to maintain cerebrovascular homeostasis. Creactive
protein(CRP) is a highly sensitive indicator of inflammation and tissue...
Journal of Turkish Clinical Biochemistry
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2020-12-01
Can Duman, Ertan Eşsizoğlu, Elif Demircan, Funda Kırtay Tütüncüler, Coşkun Bakar, Yusuf Kurtulmuş
Objective: Elevated ischemia modified albumin (IMA) and C-reactive protein (CRP) levels have been reported as a result of ischemia, which is due to atherosclerosis and increased inflammatory processes. We measured serum CRP levels and ESR to determine inflammatory status of...
Journal of Turkish Clinical Biochemistry
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2013-12-01
Emin Savaş Kılavuz, Nermin Erol
Objective: The aim of this study is to examine the effect of hypeglycemic peak induced by OGTT on
the basal inflammatory state by exploring the serum CRP level diffferencesMaterial and
Methods: I24 patients for suspicous of diabetes who have applied...
Journal of Turkish Clinical Biochemistry
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2009-08-01
Özgür Aslan, Metin Demir, Ayşenur Atay, Mehmet Hicri Köseoğlu, Mustafa Kaya
Objective: Various inflammatory molecules that are used for diagnosis and monitoring are released
into circulation when a bacterial infection is observed at host organisms. C reactive protein (CRP) is
one of these various molecules, and procalcitonin (PCT) is also an acute...
Journal of Turkish Clinical Biochemistry
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2011-08-01
Yasemin Üstündağ, Kağan Huysal, Ayşe Ulusoy Karaca, Teoman Çınar, Serpil Sancar, Müberra Akdoğan
Objective: C-reactive protein (CRP) is one of acute phase respondents that has been used to monitor
infection and inflammation episodes. In our hospitals' emergency laboratory, CRP analysis is done
with a point of care testing device (i-chroma). In our central biochemistry...
Journal of Turkish Clinical Biochemistry
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2010-04-01
Gökhan Utku, Sembol Türkmen Yıldırmak, Müberra Vardar, Ekrem Özakın, Yüksel Gülen Özbanazı, Veli Mihmanlı, Hatice Birgül Ayabakan, Hülya Çerçi
Objective: Pre-eclampsia is a pregnancy specific form of hypertension and a multisystem disorder of maternal and placental origin. Pregnancy associated plasma protein-A (PAPP-A) is a insulin like growth factor binding protein 4- degrading metalloproteinase. The aim of this...
Journal of Turkish Clinical Biochemistry
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2013-08-01
Belkız Öngen İpek, Mustafa Erinç Sitar
Objective: For this current study, our aims were to investigate the relationships between HbA1c with
neutrophil lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR) which are accepted as new
markers of systemic inflammation and the relationships between HbA1c with CRP...
Journal of Turkish Clinical Biochemistry
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2018-08-01
Burcu Barutçuoğlu, A. Erkin Bozdemir, Güneş Başol, Zuhal Parıldar, Ceyda Kabaroğlu, M. Işıl Mutaf, Oya Bayındır
Objective: The increase in serum procalcitonin (PCT) levels is a marker of severe systemic inflammation due to bacterial infection and renal excretion plays an important role in its elimination. The aim of this retrospective study is to investigate the relationship between...
Journal of Turkish Clinical Biochemistry
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2008-04-01
Derya Koçer, Fatma Mutlu Sarıgüzel, Emel Güler, Çiğdem Karakükcü, Serap Tomruk Sütbeyaz, Ahmet Gödekmerdan
Objective: Ankylosing spondilitis (AS) is a chronic inflammatory disease involving primarily the skeletal
system, the peripheral joints and extra-articular structures. C-reactive protein (CRP) and erythrocyte
sedimentation rate (ESR) are commonly used assays for measuring...
Journal of Turkish Clinical Biochemistry
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2014-08-01
Ali Rıza Şişman, Tuncay Küme, Pınar Akan, Pınar Tuncel
The use of C-reactive protein (CRP) analyses in different fields of clinical practice is increasing each day. In particular, investigations indicating the potency of C-reactive protein as a marker in predicting future coronary heart disease and cerebrovascular disease in healthy people are...
Journal of Turkish Clinical Biochemistry
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2007-04-01
Nergiz Zorbozan, Elif Fırat, Orçun Zorbozan
Aim: This study aims to evaluate repeated tests and unnecessary repeated laboratory tests based on minimum retest intervals.
Materials and Methods: Data regarding thyroid-stimulating hormone (TSH), ferritin, C-reactive protein (CRP), and erythrocyte...
Journal of Turkish Clinical Biochemistry
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2025-12-01
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DOI: 10.56615/tkbd.2025.13
Celal Kurt, Sembol Yıldırmak, Murat Usta, Ömer Emecen
Aim: The aim of this study is to investigate the possible effects of chronic smoking on serum vitamin D
and some inflammation markers.
Materials and Methods: The smoking history of a total of 110 volunteer adults, 76 females and 34
males, for whom 25...
Journal of Turkish Clinical Biochemistry
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2021-08-01
Baysal Karaca, Nuriye Uzuncan, Osman Evliyaoğlu, Ayşe Arısoy, Ayten Coşkuner, Onur Özgenç
Sepsis is defined as systhemic response against infections and frequently caused by gram negative bacteria. It is proposed that the blood levels of acute phase reactants such as Lipopolisaccharide Binding Protein (LBP), C-reactive protein (CRP), mediators of septic cells such as Tumor Necrosis...
Journal of Turkish Clinical Biochemistry
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2003-08-01
Mehmet Gürbilek, Çiğdem Damla Deniz, Mehmet Sinan İyisoy, Gamze Demirel, Nahide Baran, Mehmet Özcan
Objective: Since the emergence of Coronavirus Disease 2019 (Covid-19) in December 2019, it has
turned into a pandemic. Covid-19 infection; can trigger pulmonary inflammation and also cause acute
lung injury. In cases with severe pneumonia, long hospital stays and high...
Journal of Turkish Clinical Biochemistry
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2022-04-01
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DOI: 10.56615/tkbd.2022.06
Türkan Yiğitbaşı, Serkan Kap, Yasemin Baskın, Banu Aslan Şentürk, Nihal Kahya Eren, Füsun Üstüner, Oktay Ergene
Objective: Levels of C-reactive protein might be important, in coronary artery disease regarding
long-term risk assessment and prognosis. It has been showed that coronary artery disease is
associated with high levels of C-reactive protein whereas the relationship between...
Journal of Turkish Clinical Biochemistry
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2009-04-01
Ceyda Kabaroğlu, Ece Onur, Betül Ersoy, Bayram Özhan, Soner Erdin, Ahmet Var, Oya Bayındır
Objective: In this study, we aimed to evaulate serum C-reactive protein (CRP), interleukin 6 (IL-6),
and neopterin levels with lipoprotein phospholipase A2(Lp-PLA2) activity in obese adolescents with or
without insulin resistance, and to demonstrate their relationships with...
Journal of Turkish Clinical Biochemistry
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2011-12-01
Ayşe Basmakcı, Esra Gürdl, Ayşe Selcen Pala, Orkide Kutlu, Mine Adaş, Mustafa Şahi, Fatih İncirku, Çiğdem Arabacı, Okan Dikker
Aim: We aimed to determine the glypican-3 levels in patients diagnosed with COVID-19, compare these values with the healthy controls, and analyze the evaluation of glypican-3 levels with inflammatory markers, including interleukin-6 (IL-6), to determine its role in disease...
Journal of Turkish Clinical Biochemistry
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2023-04-01
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DOI: 10.56615/tkbd.2023.02
Raziye Topkafa, Abdullah Sivrikaya, Duygu Eryavuz Onmaz, Gulsum Abuşoğlu, Muhammet Limon, Sema Yılmaz, Ali Ünlü
Aim: Homocitrulline (Hcit) is a modified amino acid originated by carbamylation of lysine residues and
it is considered a potential biomarker in inflammatory diseases. Behçet's disease (BD) is an
autoinflammatory disease, the diagnosis of the disease is based on clinical...
Journal of Turkish Clinical Biochemistry
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2022-08-01
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DOI: 10.56615/tkbd.2022.09
Veysel Sucu, Müberra Vardar, Ralfi Singer, Mustafa Durmuşcan, Okan Dikker
Objective: Autoimmunity is an important factor in the pathogenesis of Behcet Disease emphasized in
recent years In recent studies, Vitamin D has been demonstrated to play a significant role in immune
system functioning. The measurement of plasma 25-hydroxyvitamin D3levels,...
Journal of Turkish Clinical Biochemistry
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2019-04-01
Hacer Koç, Özlem Çakır Madenci, Asuman Orçun, Nihal Yücel, Şeymanur Sağlam, Nurdan Papila Topal
Objective: We aimed to investigate the NT-proBNP levels in high fever patients without heart failure, to
contribute to the proper request and interpretation of the test.
Methods: Patients group included 31 patients who admitted with a body temperature...
Journal of Turkish Clinical Biochemistry
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2020-12-01
Ruşen Köçeroğlu, Mehmet Ramazan Şekeroğlu, Ragıp Balahoroğlu, Erdem Çokluk, Haluk Dülger
Objective: Familial Mediterranean Fever (FMF) is an autosomal recessive disease, and it is
characterized by recurrent inflammatory attacks of the serous membranes which cause periodic
abdominal pain, fever and joint pain. The physiopathology of the disease seems more complex...
Journal of Turkish Clinical Biochemistry
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2015-04-01
Güler Buğdaycı, Erdinç Serin, Fatih Özcan
Objective: Use of C-Reactive protein in the follow-up of different clinical situations is getting more important. Levels of CRP can be detected by immunonephelometric and immunoturbidimetric methods in the clinical laboratories. The emergency departmentÕs laboratory renders...
Journal of Turkish Clinical Biochemistry
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2007-08-01