Berna Yalçın, Can Duman, Mustafa B. Çekmen, Berrin Çetinarslan, Zeynep Cantürk, Sarper Erdoğan, Hacı Kahya Özdoğan, İstemihan Tengiz, Ertuğrul Ercan
Aim: The oxidative stress which is caused by free radicals can play role in emerging and/or progressing many diseases. Hyperthyroidism can induce a lot of changes dealing with the systems of nitric oxide (NO) and antioxidant systems of several tissues in increasing the...
Journal of Turkish Clinical Biochemistry
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2004-04-01
Tülin Ayşe Özden, Beyhan Ömer, Günay Saner, Haluk Saner, Mahmut Müslümanoğlu, Sıtkı Tuzlalı
Objective: Breast cancer is one of the most frequent types of cancers seen in women, especially in industrial societies. It is a heterogeneous and complex disease affected by genetic, diet and environmental factors. This study intends to investigate if there is a significant...
Journal of Turkish Clinical Biochemistry
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2004-08-01
Gamze Avcıoğlu, Yavuz Otal, Özcan Erel
Aim: Many mediators and biomarkers play a role in the pathogenesis of bacterial sepsis (BS) which is
still not fully illimunated.The aim was to analyze intracellular oxidised glutathione (GSSG)/reduced
glutathione (GSH) and serum thiol/disulfide (extracellular) homeostasis...
Journal of Turkish Clinical Biochemistry
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2022-04-01
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DOI: 10.56615/tkbd.2022.01
Gamze Avcioğlu, Yavuz Otal, Özcan Erel
Aim: Many mediators and biomarkers play a role in the pathogenesis of bacterial sepsis (BS) which is
still not fully illimunated. The aim was to analyze intracellular oxidised glutathione (GSSG)/reduced
glutathione (GSH) and serum thiol/disulfide (extracellular) homeostasis...
Journal of Turkish Clinical Biochemistry
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2021-12-01
Selçuk Kaya, Recep Sütçü, Emel Sesli Çetin, Nigar Yılmaz, Salih Arıkan, Buket Cicioğlu Arıdoğan, Namık Delibaş
Objective: The aim of the study was to investigate the relationship between viral load and lipid peroxidation and antioxidant enzymes in patients with hepatitis B virus (HBV) infection.
Materials and Methods: We examined 50 patients (26 male, 24 female)...
Journal of Turkish Clinical Biochemistry
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2006-08-01
Serpil Bayır, Sevgi Eskiocak, Şemsi Altaner, Erol Çakır
Dietary cholesterol is suggested to cause atherosclerosis and to increase the production of free radicals. It is reported that hypercholesterolemic diet may make some changes on the antioxidant system. In our study, we aimed to observe the effect of N-acetylcysteine (NAC) treatment on the...
Journal of Turkish Clinical Biochemistry
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2006-04-01
Namık Delibaş, İbrahim Kılınç
Diabetes mellitus is a metabolic disease characterized by hyperglycemia resulting from defective insulin secretion or resistance to insulin action, or both. Production of sugar alcoholes called as metabolic hypothesis, ischemia-hipoxia oxidative stress, and insufficiency of neurotrophin or...
Journal of Turkish Clinical Biochemistry
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2003-04-01
Tevfik Noyan, Ragıp Balahoroğlu, Ufuk Kömüroğlu
It has been reported that oxidative stress is increased in diabetes mellitus and the increase in oxidative stress gives rise to complications of this disease. In the present study, we aimed to investigate the effects of vitamin A, E, and C treatments combined with insulin on the oxidative and...
Journal of Turkish Clinical Biochemistry
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2004-12-01
Handan Ak Çelik, Hikmet Hakan Aydın, Ceyda Kabaroğlu, Can Duman, Ece Onur Aydemir, Oya Bayındır
Objective: Defibrotide, a polydeoxyribonucleotide, has been found to modulate endothelial cell function and to have an antithrombotic effect on arteries, veins and capillaries. A significant amonut of evidence has been found about the protective role of defibrotide in...
Journal of Turkish Clinical Biochemistry
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2006-08-01