Ahmet Çelik, Gürkan Çıkım, Edibe Sarıçiçek, Elif Şahin, Metin Kılınç
Objective: The aim of the present study is to investigate the relation between new obesity indices waist
circumference/height (WtHR), visceral adiposity index (VAI) and body adiposity index (BAI) and
homeostasis model assessment of insülin resistance (HOMA-IR) index and...
Journal of Turkish Clinical Biochemistry
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2014-04-01
Inanc Karakoyun, Fatma Demet Arslan
Aim: Pancreatic cancer (PC) is a disease with complex and poorly understood etiology. One of the
common risk factors of PC is diabetes mellitus (DM). Increased carbohydrate antigen (CA) 19-9 levels
can be used as a biomarker in diagnosis of PC. However, CA 19-9 levels have...
Journal of Turkish Clinical Biochemistry
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2020-12-01
Münasip Özinan, Banu Arslan Şentürk, Sinem Frenkçi, Füsun Üstüner
Objective: Adiponectin, is a novel adipose tissue specific protein that has structural homology collagen VIII, X and complement factor C1q. It is also shown that insulin resistance and obesity cause to diminish adiponectin extraction from human adipose tissue but the...
Journal of Turkish Clinical Biochemistry
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2008-08-01
Özlem Demirelce, Levent Deniz
Objectives: Despite various studies on the effect of thyroid status on insulin sensitivity in recent years, there are conflicting data. Thyroid dysfunction leads to changes in glucose and lipid metabolism, which is an important risk factor for cardiovascular diseases. For this...
Journal of Turkish Clinical Biochemistry
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2025-04-01
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DOI: 10.56615/tkbd.2025.04
Ahmet Solak, Pınar Tuncel
Objective: Metabolic syndrome is a comorbidity of insulin resistance, impaired glucose tolerance,
abdominal obesity, hypertension and dyslipidemia and associated with increased risk of cardiovascular
disease. The secretion of adipocytokines such as leptin and adiponectin...
Journal of Turkish Clinical Biochemistry
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2009-04-01
Ruhi Doğan, Muhammed Emin Düz, Burak Yasin Avcı, Elif Menekşe, Ecem Avcı, Alpaslan Öztürk
Aim: Polycystic ovarian syndrome (PCOS) is a multifactorial disorder with different phenotypic characteristics, the most frequent endocrine disorder in women, and the leading cause of anovulatory infertility. Kisspeptin is recognized to have a crucial function in regulating...
Journal of Turkish Clinical Biochemistry
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2024-08-01
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DOI: 10.56615/tkbd.2024.05
B.A. Şentürk, F. Üstüner, S. Aksu, Z. Sülek
Objective: Plasminogen activator inhibitor type I (PAI-1) an inhibitor of fibrinolysis and an important and independent cardiovascular risk factor, has been shown to be elevated in obesity. The aim of this study was to evaluate plasma PAI-1 levels in obese subjects and to...
Journal of Turkish Clinical Biochemistry
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2005-12-01
Ceyda Kabaroğlu, Ece Onur, Betül Ersoy, Bayram Özhan, Soner Erdin, Ahmet Var, Oya Bayındır
Objective: In this study, we aimed to evaulate serum C-reactive protein (CRP), interleukin 6 (IL-6),
and neopterin levels with lipoprotein phospholipase A2(Lp-PLA2) activity in obese adolescents with or
without insulin resistance, and to demonstrate their relationships with...
Journal of Turkish Clinical Biochemistry
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2011-12-01
Hülya Yalçin, Burak Toprak, Ayfer Çolak, Aybike Hastürk Günaslan
Objective: The discovery of vitamin D receptors and vitamin D activating enzymes in several cells other
than those involved in bone and mineral metabolism brought the non-classical effects of vitamin D into
focus. It was reported that diabetic patients have significantly...
Journal of Turkish Clinical Biochemistry
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2017-08-01
Yasemin Baskın, Türkan Yiğitbaşı, Gökan Afacan, Şengül Bağbozan
Objective: Obesity promotes the development of diseases in many organ systems. The relationship between lipoporotein (a), lipid parameters and insulin resistance which accompany obesity has not been clarified. The correction of dyslipidemia in obesity and insulin resistance is...
Journal of Turkish Clinical Biochemistry
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2008-08-01
Tuba Hancı, Hakan Türkön, Ayfer Çolak Aydoğdu, Ömür Yıldız, İsmail Karademirci, Işıl Çoker
Objective: Obesity is the leading public health problem in this century. In this study we aimed to evaluate the hsCRP levels which are the indicators of inflammation in obese people (defined with BMI) and assess the relation between obesity and hsCRP.
Materials...
Journal of Turkish Clinical Biochemistry
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2012-04-01