The official publication of Turkish Society of Clinical Biochemistry
Objective: The use of glycemic markers in the follow-up of Diabetes Mellitus is important to prevent the development of complications. Glycated hemoglobin (HbA1c) is more stable and exhibits glucose status of 8-12 weeks, while fasting plasma glucose (APG) reflects the...
Objective: Measurement of HbA1c is widely used in patients with diabetes mellitus as a monitor of retrospective glycemic control. Currently, more than 30 different methods are commercially available to measure HbA1c and these methods vary in the fraction of Hb measured and the...
Objective: For this current study, our aims were to investigate the relationships between HbA1c with neutrophil lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR) which are accepted as new markers of systemic inflammation and the relationships between HbA1c with CRP...
Purpose: Hemoglobin A1c (HbA1c), also known as glycated hemoglobin, indicates the blood glucose control over the last 8-12 weeks. HbA1c level is a useful marker for the monitoring of the diabetic patient and shows the necessity of any adjustment to the treatment has to be...
Aim: The frequency and severity of urinary tract infections (UTI) in diabetic patients are increasing. HbA1c retrospectively gives important information about glycemic control. In this study it was aimed to examine the relationships between presence of microscobic...
Aim: We aimed to demonstrate the interference in Hemoglobin A1c (HbA1c) testing in a patient diagnosed with Evans syndrome, a rare condition characterized by autoimmune hemolytic anemia.
Case: A patient who presented to our laboratory for biochemical...
Background: It has been established that hemoglobinopathies and chemically modified derivatives of hemoglobin, interfered with some HbA1c assay methods either positively or negatively. In this study we present a case with a low HbA1c value as measured by ion-exchange HPLC...
Objective: In addition to important roles of vitamin D on regulation of bone and mineral metabolism, recent studies have shown that Vitamin D is necessary for many biological actions. The aim of this study was to determine whether Vit D levels have any effects on lipid...
Objective: Method comparison experiments are based on comparison of samples results analyzed by the new test method and previously accepted method. In this study is aimed to compare reversedphase cation exchange chromatography with boronate affinity chromatography method...
Objective: A natural anticoagulant Protein C and its cofactor free Protein S, play an important role in the development of thrombosis in diabetics. In this study, we compared Protein C and Protein S concentrations in type 2 diabetic patients and healthy controls and observed...
Aim: We aimed to evaluate HbA1c with HbA0, HbF, HbA1 subfractions and to discuss the clinical usefulness of HbA1c by considering the total hemoglobin (THb) levels of the patients.
Materials and Methods: This retrospektif study included 338 individuals...
Aim: Pancreatic cancer (PC) is a disease with complex and poorly understood etiology. One of the common risk factors of PC is diabetes mellitus (DM). Increased carbohydrate antigen (CA) 19-9 levels can be used as a biomarker in diagnosis of PC. However, CA 19-9 levels have...
Aim: In this study, it was aimed to evaluate the preanalytical process performance in our laboratory with the six-sigma methodology and to investigate the effect of the training given to the hospital staff on the sigma values.
Materials and Methods:...
Objective: In this study, we aimed to evaulate serum C-reactive protein (CRP), interleukin 6 (IL-6), and neopterin levels with lipoprotein phospholipase A2(Lp-PLA2) activity in obese adolescents with or without insulin resistance, and to demonstrate their relationships with...
Objective: Cysta tin C has been proposed for the estimation of glomerular filtration rate (GFR). This study was designed to evaluate cystatin C levels in Type 2 Diabetes Mellitus (DM) as an early marker of diabetic nephropathy.
Materials and Methods:...
Objective: The discovery of vitamin D receptors and vitamin D activating enzymes in several cells other than those involved in bone and mineral metabolism brought the non-classical effects of vitamin D into focus. It was reported that diabetic patients have significantly...
Objective: There is an increase in platelet activation in diabetics and patients with diabetic complications. Labile hemoglobin A1c (LHbA1c), an early glycation product, can turn into other glucose metabolites which can be responsible for many kinds of pathologies observed...
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