Aim: Raynaud's phenomenon is characterized by transient reduction in blood supply through the small arteries in the hands and feet. Secondary Raynaud's phenomenon accompanies collagen vascular diseases such as rheumatoid arthritis and scleroderma. The relationship between...

In chronic renal failure, high plasma homocysteine levels are a common finding and in uremia almost the rule. The cause of hyperhomocysteinemia in ESRD (end stage renal disease) whether it lies in an impared renal or extrarenal metabolism or through uremic retention toxins, is still under...

Objective: In this study in which the purpose was to investigate the effect of hemodialysis treatment on cardiac markers and trace elements, serum copper, zinc, homocysteine and lipoprotein (a) levels and ceruloplasmin oxidase and adenosine deaminase activities and compared...

Objective: It has been proposed that the homocysteine (Hcy) produced during the metabolism of methionine plays a role in etiopathogenesis of several diseases. The interest in measurement of plasma Hcy levels has increased recently upon the finding that Hcy is an independent...

The vitamin B12and folic acid are water soluble vitamins the metabolisms of which are connected to each other and which are necessary for various metabolic paths in the central nervous system. These vitamins are used as cofactors in the conversion of the homocysteine, the high concentrations of...

Hyperhomocysteinemia and increased ACE activity due to the deletion polymorphism of the ACE gene are two common features in a wide variety of pathological conditions that exhibit endothelial disturbances. In this study, we examined both the I/D genotype distribution and the activity of ACE in...

Hyperhomocysteinemia is a recently recognized independent risk factor for cardiovascular diseases. Although the mechanism of vascular damage in hyperhomocysteinemia has not been completely understood, it may lead to this condition by increasing free radical production and lipid peroxidation,...