Hale Aral, Berrin Berçik İnal, Murat Usta, Pınar Tonbaklar Bilgi, Ömer Emecen, Mustafa Şahin, Güvenç Güvenen
Objective: We aimed to investigate the possible differences between the analytical assay and estimation with Friedewald formula of LDL cholesterol in patients divided into subgroups according to direct LDL cholesterol, triglyceride, total cholesterol levels,...
Journal of Turkish Clinical Biochemistry
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2008-08-01
Can Duman, Emin Alioğlu
Objective: It is well known that chronic inflammation is an important factor of the process which leads to atherosclerosis. While leading to atherosclerosis inflammation can cause acute phase response as well. CRP, serologic indicator of inflamation, synthesized in liver, is...
Journal of Turkish Clinical Biochemistry
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2006-08-01
Erdem Çokluk, Mehmet Ramazan ŞEKEROĞLU, Fatıma Betül TUNCER, M. Ramazan Akdemir
Objective: In the study, it was aimed to determine the harmony of LDL-C levels determined by
enzymatic(direct) and computational method, to have an idea about the optimal request frequency by
examining the significance of the percentage changes of repeated LDL-C measurements...
Journal of Turkish Clinical Biochemistry
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2021-04-01
Okan Dikker, Mustafa Şahin
Aim: Lipid profile is used to determine the risk of cardiovascular diseases (CVD) and to monitor
treatment. Reference change value (RCV) represents the clinical significance of the variation between the
results of two consecutive tests and laboratory test results exceeding...
Journal of Turkish Clinical Biochemistry
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2019-08-01
Erkan Söğüt, Enver Avcı, Füsun Üstüner, Erdinç Arıkan
Objective: Various algorithms for predicting coronary atherosclerosis have been established, most of which are based on large epidemiologic and cohort studies. We examined the predictive value of various clinical and biochem ical markers for angiographically defined coronary...
Journal of Turkish Clinical Biochemistry
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2006-04-01
Ahmet Solak, Pınar Tuncel
Objective: Metabolic syndrome is a comorbidity of insulin resistance, impaired glucose tolerance,
abdominal obesity, hypertension and dyslipidemia and associated with increased risk of cardiovascular
disease. The secretion of adipocytokines such as leptin and adiponectin...
Journal of Turkish Clinical Biochemistry
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2009-04-01
Derya Koçer, Selma Buldu, Mehmet Zahid Çıracı, Çiğdem Karakükcü
Objective: In addition to important roles of vitamin D on regulation of bone and mineral metabolism,
recent studies have shown that Vitamin D is necessary for many biological actions. The aim of this study
was to determine whether Vit D levels have any effects on lipid...
Journal of Turkish Clinical Biochemistry
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2016-08-01
Hicran Hiçyılmaz, Nigar Yılmaz, Recep Sütçü, Hüseyin Vural, Namık Delibaş
Objective: The aim of this study was to evaluate serum total, HDL and LDL cholesterol and triglyceride levels and nitric oxide (NO) levels in rats with dietary walnut consumption.
Materials and Methods: The rats were divided into 2 groups as a control...
Journal of Turkish Clinical Biochemistry
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2007-12-01
Semra Aksu Düzcü, Füsun Üstüner, Banu Arslan Şentürk, Serdar Deveci, Murat Yeşil
Objective: The prevalence of coronary artery disease is much higher in men than in women and sex hormones might play a role in these differences via their influence on lipid profile. However, the role of sex hormones in the relationship between male gender and cardiovascular...
Journal of Turkish Clinical Biochemistry
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2010-12-01
Pınar Bakyer, Esat Adıgüzel, Simin Rota, Nuran Sabir, Ilgaz Akdoğan, Birsen Yılmaz
Objective: The goal of this study was to investigate the correlation between the ultrasonographic measurements of subcutaneous adipose tissue thickness and serum lipid levels.
Materials and methods: Randomly selected 100 subjects (50 males and 50...
Journal of Turkish Clinical Biochemistry
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2003-12-01
Sema Uslu, Ömer Çolak, Temir Ali Demir, Asiye Berber, Güven Özdemir, Özkan Alataş
Objective: In this study in which the purpose was to investigate the effect of hemodialysis treatment on cardiac markers and trace elements, serum copper, zinc, homocysteine and lipoprotein (a) levels and ceruloplasmin oxidase and adenosine deaminase activities and compared...
Journal of Turkish Clinical Biochemistry
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2005-12-01
Sema Akgün, Halit Buğra Koca, Ahmet Kahraman, Tülay Köken
Objective: Subclinical and cli nical hypothyroidism are relatively common endocrine disorders in the general population. Subclinical hypothyroidism is defined as an elevated serum thyroid stimulating hormone (TSH) level associated with normal total or free T4 (fT4) and T3...
Journal of Turkish Clinical Biochemistry
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2007-08-01
Feray Binbaş, Nuriye Uzuncan, Dilek Aslanca, Ertan Belten, Baysal Karaca
Objective: Serum paraoxonase (PON1) is a HDL associated esterase and inhibits LDL oxidation. The oxidative modification of LDL plays an important role in the pathogenesis of atherosclerosis. In hemodialysis patients, the increased oxidative stress induces oxidative...
Journal of Turkish Clinical Biochemistry
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2005-04-01
Türkan Yiğitbaşı, Serkan Kap, Yasemin Baskın, Banu Aslan Şentürk, Nihal Kahya Eren, Füsun Üstüner, Oktay Ergene
Objective: Levels of C-reactive protein might be important, in coronary artery disease regarding
long-term risk assessment and prognosis. It has been showed that coronary artery disease is
associated with high levels of C-reactive protein whereas the relationship between...
Journal of Turkish Clinical Biochemistry
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2009-04-01
Banu Arslan Şentürk, Serkan Kap, Nihal Kahya, Oktay Ergene, Füsun Üstüner
Objective: It has been known that levels of GGT might be important, in coronary artery disease for
long-term risk assessment and determining prognosis. Relationship between coronary artery disease and levels of GGT was found whereas relationship severity of coronary artery...
Journal of Turkish Clinical Biochemistry
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2009-12-01
Banu Arslan Şentürk, Ruhan Uzun, Füsun Üstüner, Mustafa Cirit, Sadık İnce
Objective: Hyperphosphatemia and high calcium X phosphate product are significant and common risk factors of cardiovascular disease in patients with chronic kidney disease. However, the relationship is not clear between increased risk and hyperphosphatemia and elevated calcium...
Journal of Turkish Clinical Biochemistry
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2006-04-01
Evin Kocatürk, Ağgül Canik, Özkan Alataş
Purpose: Laboratory tests are very important for diagnosis and tracking of disease and usage of
laboratory testing has rised with each passing day. Unnecessary laboratory testing is one of the main
reasons for increased laboratory use. In this study, we aimed to...
Journal of Turkish Clinical Biochemistry
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2015-12-01
Münasip Özinan, Banu Arslan Şentürk, Sinem Frenkçi, Füsun Üstüner
Objective: Adiponectin, is a novel adipose tissue specific protein that has structural homology collagen VIII, X and complement factor C1q. It is also shown that insulin resistance and obesity cause to diminish adiponectin extraction from human adipose tissue but the...
Journal of Turkish Clinical Biochemistry
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2008-08-01
Ceyda Kabaroğlu, Ece Onur, Betül Ersoy, Bayram Özhan, Soner Erdin, Ahmet Var, Oya Bayındır
Objective: In this study, we aimed to evaulate serum C-reactive protein (CRP), interleukin 6 (IL-6),
and neopterin levels with lipoprotein phospholipase A2(Lp-PLA2) activity in obese adolescents with or
without insulin resistance, and to demonstrate their relationships with...
Journal of Turkish Clinical Biochemistry
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2011-12-01
B.A. Şentürk, F. Üstüner, S. Aksu, Z. Sülek
Objective: Plasminogen activator inhibitor type I (PAI-1) an inhibitor of fibrinolysis and an important and independent cardiovascular risk factor, has been shown to be elevated in obesity. The aim of this study was to evaluate plasma PAI-1 levels in obese subjects and to...
Journal of Turkish Clinical Biochemistry
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2005-12-01