Objective: The laboratory critical values are the laboratory testing results which required attention or action by the physicians. The aim of this study is to investigate the laboratory critical value notification process in our laboratory in terms of patient safety and...

Objective: The discrepancy between chemical and microscopic urine examination makes it demanding to interpret the results. We aimed to evaluate the laboratory personnels effect on the consistency between chemical and microscopic urine examination results.

Aim: The Intra-laboratory Turnaround Time (IR-TAT) serves as a significant measure of overall laboratory efficacy. This study sought to augment laboratory operational productivity and diminish IR-TAT by instating a Total Laboratory Automation (TLA) system, executing stat...

Aim: This study aimed to evaluate the distribution and trends of ethanol analysis results according to age, gender, and ethanol concentration levels over a four-year period.

Materials and Methods: In this retrospective study, a total of 11,684 ethanol...

Introduction: The disease caused by SARS-CoV-2, which the World Health Organization has considered as a pandemic, was named COVID-19 and has since spread worldwide. The COVID-19 pandemic has drastically changed the way we live and work. During events like COVID-19, it is...

Objective: Transferrin isoform analysis is performed for diagnosis of congenital or acquired defects in protein glycosylation. The reference method for transferrin isoform analysis is isoelectric focusing electrophoresis. The objective of this study has been to perform...

Objective: Hemoglobinopathies are an array of disorders that affect hemoglobin (Hb) function. HPLC is by far the most common technique used for detection of hemoglobinopathies worldwide. The aim of this study is to evaluate 3-year retrospective data of a tertiary hospital in...

Objective: In the clinical laboratories, the same test could be analyzed by more than one assay system or analyzer due to various requirements. This may cause a problem in patient monitoring. In our laboratory, stat TSH testing has been recently implemented in the stat...

Aim: The entire analytical process in forensic toxicology is defined in medical laboratory regulation, standarts and guidances. The aim of this study is to evaluate the suitability of forensic toxicological analysis to the quality management process according to different...

Aim: In the present study, we aimed to evaluate the association between disseminated intravascular coagulation (DIC) score and mortality among adult sepsis patients in intensive care unit (ICU).

Material and Methods: In this retrospective cohort study,...

Objectives: This study aims to analyze the turnaround time (TAT) of intraoperative PTH (parathyroid hormone) testing and to support surgical success with objective criteria by calculating reference change values (RCV).

Methods: TAT analysis was...

Objective: The measurement of serum alcohol level is one of the most common tests in forensic and toxicologic laboratories. Measurement uncertainty is an analytical data which evaluate the reliability of a test. This study aims to evaluate the measurement uncertainty of the...

Purpose: Oral glucose tolerance test (OGTT) is a very important procedure in diagnosing diabetes mellitus. It is very crucial to perform OGTT according to the rules that must be taken into account in preparation period of the test. Our aim was to determine the level of...

Aim: Oxysterols are derivatives of cholesterol which are formed by oxidation through numerous chemical reactions and play an important role in many physiological processes and in various degenerative and metabolic diseases, lipid metabolism disorders. In this study, analytical...

Aim: The aim of the study was to evaluate the sample rejections reasons by the quality indicators and six sigma process, to determine the acceptability of the rejection reasons and to improve them during the follow-up process.

Material and Method: The...

Objective: Thyroid function, influenced by age and sex, provides important epidemiological information when evaluated at the population level. This study aimed to investigate age- and sex-related differences in thyroid-stimulating hormone (TSH), free triiodothyronine (fT3),...

Objective: Increasing the role of laboratories in the diagnosis processes is associated with a growing number of the requested laboratory tests. However, this situation is considered as time consuming and also accompanied by an increase in costs, as well as additional...

Objective: Graves' disease is an autoimmune disease which results in excessive production of thyroid hormones and is the most common cause of hyperthyroidism. TRAb has a key role to confirm the clinical diagnosis of Graves' disease. The different measurement methods have...

Objective: HPLC (High Performance Liquid Chromatography) is the most commonly used method to differentiate the subtypes of hemoglobin in screening for hemoglobinopathy. Today, different models and trademarks of HPLC equipment have been used in screening for hemoglobinopathy....

Background: Bromcresol green (BCG) and Bromcresol Purple (BCP) which are dye-binding based methods are widely used in serum albumin analysis in clinical laboratories for many years. It was suggested that discrepancies exist between these methods and these discrepancies are...

Objective: Vitamin D has several functions in cell growth, immunity, and metabolism. Vitamin D deficiency has been associated with rickets. In deficient states, there is a higher risk for autoimmune diseases, cancers, myocardial infarction, diabetes, and infectious diseases....

Objective: If a new analyzer in the laboratories is considered to be used, method comparison should be done. Two analyzers should be compared in order to evaluate accuracy of the new analyzer. In our study, we aimed to compare the performance of new coagulation analyzer with...

Aim: Point Of Care (POC) tests are quick tests that shorten the treatment period and are portable devices, which are easy to use for non-laboratory personnel. In this study we aimed to compare the results of INR (International Normalized Ratio) that were studied with POC...

Objective: Since the emergence of Coronavirus Disease 2019 (Covid-19) in December 2019, it has turned into a pandemic. Covid-19 infection; can trigger pulmonary inflammation and also cause acute lung injury. In cases with severe pneumonia, long hospital stays and high...

Aim: Immunofixation electrophoresis (IFE) is a gold standard biochemical technique used in the diagnosis, treatment and follow-up of monoclonal gammopathies. In paraproteinemias, excessive production of immunoglobulins (Ig) known as paraprotein or monoclonal protein...