Mehmet Gürbilek, Çiğdem Damla Deniz, Mehmet Sinan İyisoy, Gamze Demirel, Nahide Baran, Mehmet Özcan
Objective: Since the emergence of Coronavirus Disease 2019 (Covid-19) in December 2019, it has
turned into a pandemic. Covid-19 infection; can trigger pulmonary inflammation and also cause acute
lung injury. In cases with severe pneumonia, long hospital stays and high...
Journal of Turkish Clinical Biochemistry
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2022-04-01
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DOI: 10.56615/tkbd.2022.06
Leyla Öz, Derya Koçer, Selma Buldu, Çiğdem Karakükcü
Objective: Errors in clinical laboratories have an important effect on safety and care of patients. Thus,
causes of specimen rejections should be identified and corrected to guarentee quality results. The
objectives of this study were to identify and classify the causes of...
Journal of Turkish Clinical Biochemistry
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2016-04-01
Giray Bozkaya, Murat Örmen, Sibel Bilgili, Murat Aksit
Objective: Familial Mediterranean fever (FMF) is an autosomal recessive hereditary disease
characterised by recurrent attacks of serositis and fever accompanied by pain in the abdomen. FMF is
caused by mutations in Mediterranean Fever (MEFV) gene. The aim of this study was...
Journal of Turkish Clinical Biochemistry
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2016-08-01
Gökhan Çakırca, Mehmet Akif Bozdayı
Aim: To evaluate urine integrity tests performed before illegal and abused substance analysis and to reveal their limitations.
Materials and Methods: This retrospective study was conducted between January 1, 2023 and June 15, 2023, in the AMATEM...
Journal of Turkish Clinical Biochemistry
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2024-08-01
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DOI: 10.56615/tkbd.2024.11
Yasemin Üstündağ, Kağan Huysal, Nilüfer Eren, Hatice Sanlı Avcı, Ayşe Ulusoy Karaca, Özdemir Özkan, Gülsevil Tarakçı, Serpil Sancar, Serap Şenel İbiş
Objective: IUrinary tract infection (UTI) is a common disease in children. Rapid and reliable diagnosis of UTI is mandatory for the prevention of complications. The aim of the present study was to assess whether or not automated urine analysis can be used as a rapid diagnostic...
Journal of Turkish Clinical Biochemistry
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2013-12-01
Ferhat Demirci, İnanç Karakoyun, Can Duman, Fatma Demet Arslan, Defne Özbek, Dilek Kalenci
Objective: Thyroid function tests (TFT) are the most frequently requested endocrine tests from clinical
laboratories. Although the guidelines published by the American and British Thyroid Associations
suggest the use of thyroid stimulating hormone (TSH) as a first step test...
Journal of Turkish Clinical Biochemistry
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2017-08-01
Özgür Baykan
Aim: Vitamin D deficiency is a common public health problem in our country. It is possible to find data
reaching 90% in studies about determining deficiency prevalence. In recent years, this deficiency has
been attracted the attention of the press and has directed people to...
Journal of Turkish Clinical Biochemistry
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2019-08-01
Güler Buğdaycı, Erdinç Serin, Fatih Özcan
Objective: Use of C-Reactive protein in the follow-up of different clinical situations is getting more important. Levels of CRP can be detected by immunonephelometric and immunoturbidimetric methods in the clinical laboratories. The emergency departmentÕs laboratory renders...
Journal of Turkish Clinical Biochemistry
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2007-08-01
Nergiz Zorbozan, Gökçe Filiz Atikeler, İlker Akarken
Aim: Laboratory results have an important effect on the clinical decision-making process. For this
reason, the analysis and reporting quality of the tests is extremely important. Measurement uncertainty
is the quantitative expression of the quality of test results. It is...
Journal of Turkish Clinical Biochemistry
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2018-12-01
Hamit Yaşar Ellidağ, Esin Eren, Özgür Aydın, Funda Savaş, Necat Yılmaz
Objective: High Performance Liquid Chromatography (HPLC) is widely used to classify hemoglobin
fractions in screening of hemoglobinopathies. We, here in this study, detected the “measurement
uncertainty” of the pivotal parameter in thalassemia screening, namely HbA2; and...
Journal of Turkish Clinical Biochemistry
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2014-04-01
Uğur Atik, M. Burak Y. Çimen
Objectives: There are not enough studies based on laboratory results regarding the prevalence of
Substance Use Disorders in our country, The purpose of this retrospective study is; to determine the
distribution of the substances used by dependent individuals with treatment...
Journal of Turkish Clinical Biochemistry
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2020-08-01
Şeniz Korkmaz
Aim: In this study, we aimed to evaluate the preanalytical process performance by six sigma method
and make the necessary arrangements according to the obtained results in our laboratory.
Materials and Methods: The total number of samples, and rejected...
Journal of Turkish Clinical Biochemistry
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2020-04-01
Tuncay Küme, Elif Güler Kazancı, Alper Cihan, Muhammed Ertuğrul Eğin, Yasemin Şenol, Ahmet Aydınlı, Yeşim Hamurtekin, Alain G. Verstraete, Belgin Ünal, Hakan Kalafat, Mukaddes Gürler, Aslı Pınar, Mehmet Şeneş, Çiğdem Kararkükcü, Hatice Topsakal, Ferzane Mercan, Eyüp Gümüş
Background: The aim of this study is to assess the results of inspections in the last three years on
drug abuse testing in medical laboratories according to the last regulations in Turkey.
Materials and Methods: The on-site inspections of medical...
Journal of Turkish Clinical Biochemistry
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2018-12-01
Saliha Aksun, Başak Bağcı, Leyla Demir, Oğuz Karalar, Murat Aksun
In drug and stimulant studies it is very important to keep the preanalytical phase controlled by the
laboratory specialist. In this process, it would be most appropriate to cooperate with the clinical unit
requesting the analysis and to plan the appropriate conditions and workflows together....
Journal of Turkish Clinical Biochemistry
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2022-12-01
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DOI: 10.56615/tkbd.2022.18
Gülsüm Feyza Türkeş, Serkan Yıldız, Özlem Gürsoy Doruk, Pembe Keskinoğlu, Tuncay Küme, Ali Rıza Şişman
Aim: Since glomerular filtration rate (GFR) determined by 24 hours urine is cumbersome, nephrologists recommend using an estimated GFR (eGFR). This study aimed to investigate the agreement between Modification of Diet in Renal Disease (MDRD) and Chronic Kidney Disease...
Journal of Turkish Clinical Biochemistry
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2023-04-01
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DOI: 10.56615/tkbd.2023.05
Yasemin Üstündağ, Kağan Huysal, Ayşe Ulusoy Karaca, Teoman Çınar, Serpil Sancar, Müberra Akdoğan
Objective: C-reactive protein (CRP) is one of acute phase respondents that has been used to monitor
infection and inflammation episodes. In our hospitals' emergency laboratory, CRP analysis is done
with a point of care testing device (i-chroma). In our central biochemistry...
Journal of Turkish Clinical Biochemistry
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2010-04-01
Fatma Demet Arslan İnce, Banu Arslan Şentürk, Hamit Ellidağ, Serkan Kap, Füsun Üstüner
Objective: Troponin I is a reliable and sensitive marker which is used to evaluate the myocardial injury. However there are different cut-off values for Troponin I due to different measurement technics. Therefore it is recommended that laboratories must define their own...
Journal of Turkish Clinical Biochemistry
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2007-08-01
Meltem Yardim, Levent Deniz, Damla Kayalp, Nilüfer Celik, Burcu Ulas Kahya
Aim: It was aimed to determine predictive markers for the need for intensive care unit (ICU) hospitalization in patients with coronavirus infection.
Material and Methods: This study was performed retrospectively from data of patients hospitalized with...
Journal of Turkish Clinical Biochemistry
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2023-08-01
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DOI: 10.56615/tkbd.2023.14
Hülya Ünal, Ayşenur Atay, Erkan Söğüt, Leyla Demir, Saliha Aksun, Recep Sütçü
Objective: Anemia is a commonly encountered health problem. In this study, togetherness of beta
thalassemia trait with iron deficiency anemia was investigated using by some biochemical and
hematological cell count indices.
Material and Methods: The...
Journal of Turkish Clinical Biochemistry
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2015-04-01
Tuncay Küme, Çiğdem Karakükcü, Nilgün Kara Uzun, Aslı Pınar
In this article, an evaluation about drug abuse testing in the clinical laboratories was done. Ministry of
Health has made arrangements for drug abuse testing in laboratory-related services; according to final
tasks from Rule of Medical Laboratories and the National Emergency Action Plan...
Journal of Turkish Clinical Biochemistry
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2016-04-01
Sema Nur Ayyıldız
Objective: Test analyses in laboratories must leave neither clinician nor patient in doubt. Measurement
uncertainty must therefore be studied for all tests in laboratories. The aim of this study was to calculate
the measurement uncertainty of the hormone...
Journal of Turkish Clinical Biochemistry
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2016-08-01
Giray Bozkaya, Öznur Asil, Kaan Kuzu
Aim: Measurement uncertainty provides information about the limits at which the measured value may vary as a result of random effects in a biochemical measurement. It is a quantitative indicator of the quality of the result obtained and allows us to estimate the extent to...
Journal of Turkish Clinical Biochemistry
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2023-04-01
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DOI: 10.56615/tkbd.2023.01
Kaan Kuzu, Giray Bozkaya
Aim: Hereditary thrombophilia is a condition where there is an increased tendency for clot formation due to a genetic variation in the coagulation system. Genetic testing in cases with a preliminary diagnosis of thrombophilia is necessary to confirm the diagnosis, eliminate...
Journal of Turkish Clinical Biochemistry
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2024-08-01
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DOI: 10.56615/tkbd.2024.07
Fatıma Betül Tuncer, Erdem Çokluk, Mehmet Ramazan Şekeroğlu, Fatma Özdemir, Meltem Boz
Objective: The aim of this study is to investigate the compatibility of bicarbonate (HCO3-) levels
measured by blood gas meter in serum autoanalyser.
Materials and Methods: In the study, serum bicarbonate and blood gas bicarbonate levels of 186...
Journal of Turkish Clinical Biochemistry
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2019-12-01
Mehmet Akif Bildirici
Objective: To compare the analytical performance of 2 immunoturbidimetric C-reactive protein (CRP) reagents using the same automated analyzer and to evaluate whether an alternative reagent provides clinically acceptable results.
Methods: This...
Journal of Turkish Clinical Biochemistry
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2026-08-25
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DOI: 10.65717/jtcb.2026.26023