The official publication of Turkish Society of Clinical Biochemistry
Objective: To compare the analytical performance of 2 immunoturbidimetric C-reactive protein (CRP) reagents using the same automated analyzer and to evaluate whether an alternative reagent provides clinically acceptable results.
Methods: This...
Aim: We aimed to evaluate HbA1c with HbA0, HbF, HbA1 subfractions and to discuss the clinical usefulness of HbA1c by considering the total hemoglobin (THb) levels of the patients.
Materials and Methods: This retrospektif study included 338 individuals...
Objective: In quantitative analysis of serum proteins turbidimetric and nephelometric methods are the most common. Aim of this study was to compare the nephelometric method with the turbidimetric method for serum and urine samples in our clinical laboratory and to analyse...
Objective: The aim of this survey was to investigate the problems of the newly graduated clinical biochemistry specialists (0-5 years of graduation) working at peripheral hospitals and to determine inadequacies of the specialty training.
Materials and Methods:...
Purpose: Rejection of unsuitable samples is important for the quality of the laboratory results. In our study, it is aimed to perform sample rejection analysis of blood samples from outpatient, inpatient and emergency units and to evaluate the effectiveness of the training...
Aim: In this study, it was aimed to evaluate the preanalytical process performance in our laboratory with the six-sigma methodology and to investigate the effect of the training given to the hospital staff on the sigma values.
Materials and Methods:...
Aim: In this study, it was aimed to examine the changes of activated partial thromboplastin time (APTT), prothrombin time (PT), and plasma fibrinogen during the day, which are the most used coagulation tests in daily routine.
Material and Methods: Blood...
Purpose: Preanalytical phase is the most common source of laboratory errors. Preanalytical errors generally cause unsuitable samples for analysis. This study was aimed to evaluate prevalence and type of rejected samples using six sigma as well as to determine the prevalence...
Objective: Uncertainty is a parameter that characterize a range which includes a measurable substantiality. It also shows how much the result represents the real value. Uncertainty of measurement comprises many components. The purpose of this study was to estimate uncertainty...
Objective: This study aimed to evaluate the frequency of repeat lipoprotein(a) testing, determine whether repeated measurements changed risk classification, assess the clinical significance of observed changes using the reference change value, and investigate whether the...
Objective: Although there have been many studies about the pre-analytic errors of hemolysis on laboratory tests, different results were found with different work environments and different methods. This study was put together to investigate the effects of hemolysis on routine...
Objective: The purpose of this study is to determine the median values of the triple test screening parameters in pregnancy in Bingöl region, and to compare the median values determined for the currently used programs and some other provinces.
Material and...
Objective: The synthesis of matrix metalloproteinase-1 (MMP-1) which is claimed to cause early mortal damage during the first moments of coronary reperfusion, is reported to be induced in-vitro by oxidized low density lipoprotein (LDL). The in- vivo changes in MMP-1, it's...
Objective: Various algorithms for predicting coronary atherosclerosis have been established, most of which are based on large epidemiologic and cohort studies. We examined the predictive value of various clinical and biochem ical markers for angiographically defined coronary...
Objective: The goal of this study was to investigate the correlation between the ultrasonographic measurements of subcutaneous adipose tissue thickness and serum lipid levels.
Materials and methods: Randomly selected 100 subjects (50 males and 50...
Objective: It is generally a gruelling job to diagnose the appendicitis, the most common cause of a surgical operation in childhood. In this study, we aimed to reveal the relationship between the values obtained by the preoperative Complete Blood Count, and the Neutrophile...
Objective: There is an increase in platelet activation in diabetics and patients with diabetic complications. Labile hemoglobin A1c (LHbA1c), an early glycation product, can turn into other glucose metabolites which can be responsible for many kinds of pathologies observed...
Objective: Various inflammatory molecules that are used for diagnosis and monitoring are released into circulation when a bacterial infection is observed at host organisms. C reactive protein (CRP) is one of these various molecules, and procalcitonin (PCT) is also an acute...
Fully Diamond OA with no APCs and no submission fees. Your research is freely available to readers worldwide from the day it publishes.
Double-blind peer review from an active editorial team returns a first decision in about 30 days, keeping your manuscript moving.
Backed by the Turkish Society of Clinical Biochemistry, JTCB welcomes submissions from researchers worldwide and reaches an international laboratory audience.
Method validation, analyzer comparisons, reference intervals, quality indicators, preanalytical studies, and instructive clinical case reports.
All manuscripts publish in English and follow ICMJE and COPE guidelines, with Crossref DOIs and TR Dizin indexing ensuring global discoverability.