Objective: A natural anticoagulant Protein C and its cofactor free Protein S, play an important role in the development of thrombosis in diabetics. In this study, we compared Protein C and Protein S concentrations in type 2 diabetic patients and healthy controls and observed...

Objective: Oxidative stress is suggested to play key role in the pathogenesis of inflammatory bowel diseases. Protein oxidation resulting from oxidative damage is notified in ulcerative colitis which is the one of the inflammatory bowel diseases. The aim of the study was to...

Objective: It has been reported that liver oxidative stress increases in streptozotocin induced experimental diabetes. The aim of this study is to investigate the effects of L-carnitine possessing antioxidant activity on liver protein oxidation seen in diabetes.

...

Objective: Pre-eclampsia is a pregnancy specific form of hypertension and a multisystem disorder of maternal and placental origin. Pregnancy associated plasma protein-A (PAPP-A) is a insulin like growth factor binding protein 4- degrading metalloproteinase. The aim of this...

Traumatic Brain Injury (TBI) is described as the brain damage occured by direct and indirect forces. Although TBI is a common health care problem, its diagnosis, management and the prediction of prognosis still remain obscure.S100B, neuron specific enolase (NSE), Glial fibrillary acidic protein...

Objective: Levels of C-reactive protein might be important, in coronary artery disease regarding long-term risk assessment and prognosis. It has been showed that coronary artery disease is associated with high levels of C-reactive protein whereas the relationship between...

The reference method for the determination of urinary protein excretion in patients with kidney diseases is the measurement of 24-h protein excretion. But 24-h. urine collection is unreliable and cumbersome. So protein/creatinine ratio (P/C) in spot urine is used to determine proteinuria. In this...

Purpose: We aimed to investigate pentraxin 3 and placental protein 13 levels related to the pathogenesis of the disease, as well as albumin, lactate dehydrogenase, uric acid and platelet count values, which are frequently requested laboratory tests, in second and third...

Objective: Analytical reliability of clinical laboratories may be obtained by internal quality control, external quality control by analyzing the data with statistical methods. In Six Sigma Methodology, which is one of these methods, the analytical performance of the tests...

Serum protein electrophoresis (SPEP) is the first line test in the diagnosis of a wide range of diseases including multiple myeloma, that are classified as monoclonal gammopathies. The test is one of the best fitting to the clinical title of the clinical biochemists as it urges the complete...

Under the physiological conditions, protein excretion in urine is less than 150 mg per day. Proteinuria is defined as an excessive rate of protein excretion in the urine. Measurement of proteinuria and identification of its components are important for the diagnosis of various clinical settings....

Trombomodulin (TM) is a 557 amino acid a glycosylated transmembrane protein and is a thrombin receptor located on endothelial cell surface. It was named as thrombomodulin due to its modulator role on the functions of thrombin. While a part of TMÕs physiological functions are through the activity...

Objectives: Protein energy malnutrition and inflammation are among the causes of morbidity in patients with metabolic stress. Because of the adipogenic and somatotrophic effects of insulin, insulin like growth factor-1(IGF-1) and insulin like growth factor binding protein-3...

The use of C-reactive protein (CRP) analyses in different fields of clinical practice is increasing each day. In particular, investigations indicating the potency of C-reactive protein as a marker in predicting future coronary heart disease and cerebrovascular disease in healthy people are...

Objective: The aim of this study is to research relations between first hour glucose and insuline level and inflamation markers in individuals who was loaded 75 grams glucose.

Materials and Methods: 11 individuals who were non obese and normal glucose...

Objective: This study aimed to evaluate the agreement between albumin measurements obtained via capillary zone electrophoresis (CZE) and bromocresol green (BCG) methods and to determine their interchangeability in clinical practice. Additionally, it explored how these results...

Aim: Immunofixation electrophoresis (IFE) is a gold standard biochemical technique used in the diagnosis, treatment and follow-up of monoclonal gammopathies. In paraproteinemias, excessive production of immunoglobulins (Ig) known as paraprotein or monoclonal protein...

Objective: Various inflammatory molecules that are used for diagnosis and monitoring are released into circulation when a bacterial infection is observed at host organisms. C reactive protein (CRP) is one of these various molecules, and procalcitonin (PCT) is also an acute...

Objective: After proving that chronic low grade inflammation is an important component of atherosclerotic process, C-reactive protein (CRP) has been started to be used for atherosclerotic vascular disease risk determination together with the other risk factors. In practice, to...

Mikro-RNAs are functional, non-protein coding RNA molecules and their transcriptions provided by intron or exon regions of the genome and non-protein coding regions of RNA genes. Mikro-RNAs inhibit translation of protein and / or cause destruction of mRNA. Most of studies have demonstrated that...

Objective: In this study, we aimed to show whether conditions which cause positive results in 50 gr gestational diabetes screening test also increase the levels of inflammatory markers in pregnant women.

Materials and Methods: Fasting fibrinogen and...

Objective: Various algorithms for predicting coronary atherosclerosis have been established, most of which are based on large epidemiologic and cohort studies. We examined the predictive value of various clinical and biochem ical markers for angiographically defined coronary...

Objective: N-acetyl-β-D-glucosaminadase (NAG) is a enzyme which exists in the lysosomes of renal proximal tubular cells. Increased NAG activity in urine is accepted as non-invasive early index of tubular damage. Lupus nephritis is known to be the most important complication of...

Aim: Smoking is accepted as a risk factor for primary chronic diseases such as cardiovascular diseases and respiratory system diseases and for cancer development. The aim of this study was to indicate the increase in inflammation in smokers by using high-sensitivity...

Objective: Ascorbic acid is endogenously converted to oxalate and appears to increase the absorption of dietary oxalate, supplementation may increase the risk of kidney stones. In this study is aimed to investigate the relation between the calcium oxalate crystals and urinary...