Recent research, concentrating on the significance of L-arginine, a basic amino acid, with respect to medical biochemistry is noteworthy. The fact that L-arginin is a nitrogen donor in nitric oxide (NO) biosynthesis provokes interest toward this amino acid. In healthy adults arginine is not...

Aim: To determine the current median values for hormone parameters used in first trimester screening test for Kayseri province and to compare the median values with those in the software used for reporting of screening test and those detected for other regions found with...

Aim: We aimed to determine the glypican-3 levels in patients diagnosed with COVID-19, compare these values with the healthy controls, and analyze the evaluation of glypican-3 levels with inflammatory markers, including interleukin-6 (IL-6), to determine its role in disease...

Background: The evaluation of pre-analytical, analytical and post-analytical phases is very important to obtain accurate, price and comparable results. Quality indicators are generally used to evaluate these processes. The present study aimed to evaluate the analytical phase...

Galectin-3 is a multifunctional protein that plays a critical role in inflammation, apoptosis, and fibrosis. It is considered a biomarker and therapeutic target in cardiovascular and neurodegenerative diseases, as well as pulmonary, hepatic, and renal fibrosis. Additionally, it is associated with...

Objective: For this current study, our aims were to investigate the relationships between HbA1c with neutrophil lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR) which are accepted as new markers of systemic inflammation and the relationships between HbA1c with CRP...

Aim: The aim was to determine if the malondialdehyde (MDA) and advanced oxidation products of protein (AOPPs) levels, which are oxidative stress parameters, can be used to determine the degree of coronary artery disease.

Materials and Methods: The...

Aim: The aim of this study was to investigate whether there is a difference in the amount of free folate that is unbound to the folate binding protein (FBP) in breast milk of preterm and term delivery groups, and the course of lactation in the first 28 days.

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Objective: Transferrin isoform analysis is performed for diagnosis of congenital or acquired defects in protein glycosylation. The reference method for transferrin isoform analysis is isoelectric focusing electrophoresis. The objective of this study has been to perform...

Objective: The purpose of our study was to determine the median values of the triple test screening parameters in pregnancy in our region.

Material and Methods: In this study we evaluated the serum alpha feto protein (AFP), unconjugated estriol (uE3)...

Aim: We aimed to evaluate HbA1c with HbA0, HbF, HbA1 subfractions and to discuss the clinical usefulness of HbA1c by considering the total hemoglobin (THb) levels of the patients.

Materials and Methods: This retrospektif study included 338 individuals...

Neutrophil gelatinase-associated lipocalin (NGAL), is a small, robust protein expressed by neutrophils and various epithelia, including the renal proximal tubules. While initially proposed as a marker for infections and certain adenocarcinomas, it is now apparent that its early and dramatic rise...

Purpose: To assess the role of NMP22 and cytology in diagnosing primary and recurrent bladder cancer and to compare the sensitivity, specificity, positive and negative predictive values, accuracy by means of staging, grading, dimensions and the number of the tumours.

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Objective: Familial Mediterranean Fever (FMF) is an autosomal recessive genetic disease that primarily affects populations surrounding the Mediterranean basin. The gene linked to FMF, called MEFV, encodes a 781-aa protein called pyrin (Marenostrin). MEFV locates on to the...

Objective: Elevated ischemia modified albumin (IMA) and C-reactive protein (CRP) levels have been reported as a result of ischemia, which is due to atherosclerosis and increased inflammatory processes. We measured serum CRP levels and ESR to determine inflammatory status of...

Objective: There is an increase in platelet activation in diabetics and patients with diabetic complications. Labile hemoglobin A1c (LHbA1c), an early glycation product, can turn into other glucose metabolites which can be responsible for many kinds of pathologies observed...

Objective: Method comparison experiments are based on comparison of samples results analyzed by the new test method and previously accepted method. In this study is aimed to compare reversedphase cation exchange chromatography with boronate affinity chromatography method...

Objective: Nicotine is an important component of cigarette smoke. Nicotine administration may result in oxidative stress by inducing the generation of reactive oxygen species in the periphery and central nervous system. Numerous epidemiological studies have demonstrated an...

Aim: Physical, sexual, biological, psychological and social changes occur in the adolescent period. Vitamin D is an anti-inflammatory hormone that regulates the body's calcium (Ca) and phosphorus (P) balance, provides bone development, contributes to the formation of the...

Purpose: Urinary tracts infections (UTI) are the most common cause of bacterial and hospital based infections. The gold standard in the diagnosis of UTI is urine culture. Patients with suspected UTI are usually requested for urinalysis simultaneously with urine culture. In...

Objective: Colorectal cancer is one of the most endemic cancers causing significant health problems which decreases life quality and causes job loss. As in several cancer types, it is assumed that oxidative damage and consequent inşammation may have an effect on colorectal...

Purpose: End-stage renal disease; is a disease characterized by loss of renal function where inflammation is involved in its pathogenesis. Adiponectin is an anti-inflammatory protein secreted from the adipose tissue. ICAM-1 and VCAM-1 are vascular adhesion molecules that...

Objective: It has been known that levels of GGT might be important, in coronary artery disease for long-term risk assessment and determining prognosis. Relationship between coronary artery disease and levels of GGT was found whereas relationship severity of coronary artery...

Fatty acid-binding proteins (FABPs) are abundant 14-15-kDa cytoplasmic proteins expressed in almost all mammalian tissues. They coordinate lipid responses in cells and related with metabolic and inflammatory pathways. FABPs bind to hydrophobic ligands, such as saturated and unsaturated long-chain...

Objective: Adiponectin, is a novel adipose tissue specific protein that has structural homology collagen VIII, X and complement factor C1q. It is also shown that insulin resistance and obesity cause to diminish adiponectin extraction from human adipose tissue but the...