Biological thiols are one of the most important anti-oxidant defense mechanism in protecting cells against oxidative stress. Their determination in biological materials is carried out mainly by different spectrophotometric assays. In this study; one of the commonly used spectrophotometric assay...

Aim: Six Sigma is a quality management tool that helps continuously monitor and improve the performance of the tests in the clinical laboratory. The quality goal index (QGI) ratio represents the state of meeting the respective quality targets of both bias and precision. The...

There is no a standart pr ocedure to assess instrument quality on technical and analytical performance of glucometers yet. We made up our protocole considering NCCLS EP9-A2 (National Commitee for Clinical Laboratory Standarts EP9-A2) and ISO 15197 (International Organization for Standardization...

Objective: Combine test (between the 11 th and 14th weeks of gestation) and triple test (between the 16 th and 18th weeks of gestation) are being used for trisomy 21 and trisomy 18 screening. We have investigated the precision of fetal nuchal translucency (NT), free β HCG...

Objective: C-reactive protein (CRP) is one of acute phase respondents that has been used to monitor infection and inflammation episodes. In our hospitals' emergency laboratory, CRP analysis is done with a point of care testing device (i-chroma). In our central biochemistry...

Aim: This study aimed to evaluate the performance characteristics of preliminary coagulation tests on the Sysmex CS-5100 coagulation autoanalyzer and compare it with the ACL Top 700 autoanalyzer. Both analyzers were assessed for their ability to measure prothrombin time (PT),...

Objective: Use of C-Reactive protein in the follow-up of different clinical situations is getting more important. Levels of CRP can be detected by immunonephelometric and immunoturbidimetric methods in the clinical laboratories. The emergency departmentÕs laboratory renders...

Screening for fecal occult blood has been shown to be effective in reducing the colorectal cancer mortality. Guaiac-based tests are one of the most frequently used screening tests, but their false positivity and negativity rates are quite high. Peroxidase enzyme, found in many fruits and...

Aim: Method evaluation studies should be carried out for every new method planned to be used in laboratories. The aim of this study is to determine the analytical performance of the immunoassay method used for determining of plasma 25-hydroxy vitamin D levels and also to...

Objective: Measurement of HbA1c is widely used in patients with diabetes mellitus as a monitor of retrospective glycemic control. Currently, more than 30 different methods are commercially available to measure HbA1c and these methods vary in the fraction of Hb measured and the...