The official publication of Turkish Society of Clinical Biochemistry
Background: Beta-human chorionic gonadotropin (beta-hCG) is secreted in small amounts by all cells and since the hormone is largely excreted by the kidneys, its levels can be elevated in non-pregnantdialysis patients.
Case presentation: A 27-year-old...
Aim: During pregnancy, metabolic and oxidative changes are seen, including various trace elements and oxidative stress. The main purpose of this study was to evaluate zinc, copper concentrations and oxidative status compared to trimesters in normal pregnancy.
...Objective: The purpose of this study was to determine the correlation of between second-trimester maternal serum alphafetoprotein, human chorionic gonadotropin b, unconjugated estriol levels and pregnancy complications.
Material and Methods: The data...
Objective: In this study we aimed to calculate the median levels of free β-hCG and PAPP-A levels of pregnant women in our area and to search the relationship between the pregnancy complications and these medians.
Material and Methods: The serum free...
Objective: Pre-eclampsia is a pregnancy specific form of hypertension and a multisystem disorder of maternal and placental origin. Pregnancy associated plasma protein-A (PAPP-A) is a insulin like growth factor binding protein 4- degrading metalloproteinase. The aim of this...
Aim: Diagnosis and treatment of thyroid disorders are essential for a healthy pregnancy. Physiologic changes that occur during pregnancy affect the functioning of the thyroid gland and thyroid function tests. The aim of this study was to determine the reference ranges of...
Aim: Immature granulocytes, an indicator of increased myeloid cell production, are associated with infection or systemic inflammation. Data on the use of immature granulocyte levels as a biochemical marker in infection and inflammatory conditions have been reported. In our...
Background: First trimester prenatal screening gives the risk rates associated with aneuploidies. Measurement uncertainty is defined as a magnitude showing distribution of the measured values. The aim of this study is to investigate the effects of measurement uncertainty on...
Aim: The aim of this study was (1) to compare the serum insulin, ghrelin, obestatin and, copeptin levels between pregnant and non-pregnant women and (2) investigate the changes in these parameters in pregnant women that measured at before and second hour after 75 gram (g)...
Objective: In this study, we aimed to investigate the importance of serum pregnancy associated plasma protein A (PAPP-A) levels as an early marker before an acute myocardial infarction due to a high risk atherosclerotic plaque rupture and the relationship between PAPP-A and...
Objective: Preeclampsia is characterized with edema, proteinuria and hypertension and develops after the 20th week of pregnancy and seen only in pregnancy. In preeclampsia vasospastic ischemia and hypertension can lead to brain, liver and renal infarction. One of the renal...
Objective: The purpose of this study is to determine the median values of the double test screening parameters in Bursa region and to reevaluate the test results positive risky pregnancies according to previous computer programme.
Materials and Methods:...
Objective: First trimester screening tests are widely used for the diagnosis of chomosomal anomalies. In our study, we investigated the effect of maternal smoking on first trimester screening tests in pregnant women who applied to our laboratory.
Material and...
Objective: Combine test (between the 11 th and 14th weeks of gestation) and triple test (between the 16 th and 18th weeks of gestation) are being used for trisomy 21 and trisomy 18 screening. We have investigated the precision of fetal nuchal translucency (NT), free β HCG...
Objective: Gestational diabetes mellitus is one of the most frequent complications in pregnancy which may create a health risk for the mother and the child. Different criteria may be used in the diagnosis of gestational diabetes mellitus. In the present study we aimed to test...
Objective: The purpose of our study was to determine the median values of the triple test screening parameters in pregnancy in our region.
Material and Methods: In this study we evaluated the serum alpha feto protein (AFP), unconjugated estriol (uE3)...
Objective: The aim of this study was to evaluate the effects of nicotine on myocardium of newborn rats whose mothers received nicotine during gestation and lactation, by using biochemical and pathological parameters and to evaluate the role of antioxidant enzymes, free oxygen...
Aim: To determine the current median values for hormone parameters used in first trimester screening test for Kayseri province and to compare the median values with those in the software used for reporting of screening test and those detected for other regions found with...
Objective: The unnecessary test requesting has significant effect in the laboratory workload. The unnecessary demand and the additional cost of performed tests were discussed through the anemia approach algorithm.
Materials and Methods: We...
Aim: The uncertainty of measurement is an important indicator for both the expediency of a method and the reliability of analytical results obtained in a laboratory. Accreditation processes such as ISO 15189 also expect laboratories to have a defined method for measurement...
Objective: The purpose of this study is to determine the median values of the triple test screening parameters in pregnancy in Bingöl region, and to compare the median values determined for the currently used programs and some other provinces.
Material and...
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