Aim: Measurement of cardiac troponins is of great importance in the diagnosis and follow-up of acute myocardial infarction. The diagnostic specificity of myocardial infarction has increased with algorithms including serial troponin measurements. It is important that the...

Objective: In this study we aimed to calculate the reference intervals of carbohydrate antigen 15-3 (CA15-3), carbohydrate antigen 19-9 (CA19-9), carbohydrate antigen 125 (CA125) and carsinoembriyogenic antigen (CEA).

Materials and Methods: 325 healthy...

Aim: Reference intervals/ranges are the most widely used decision-making tool in laboratory medicine and serve as the basis for many of the interpretations of test results. There is no agreement on the reference (normal) ranges for serum total 25-hydroxyvitamin D (25(OH)D)...

Purpose: The maturation of hemostatic system continues from fetal life to adult. Determination of agedependent reference ranges for coagulation is therefore very important to evaluate correctly the hemostasis. The study aimed to establish age-dependent reference range for...

Purpose: The purpose of this study is to determine serum B12 and folic acid reference values that can be used in our hospital district population.

Materials and Methods: 300 healthy individuals were chosen according to CLSI Approved Guideline C28-A....

Purpose: The aim of this study is to determine the activated partial thromboplastin time (aPTT), prothrombin time (PT), international normalized ratio (INR) reference values to be used in our hospital population.

Materials and methods: In this study,...

Aim: Immature granulocytes, an indicator of increased myeloid cell production, are associated with infection or systemic inflammation. Data on the use of immature granulocyte levels as a biochemical marker in infection and inflammatory conditions have been reported. In our...

Objective: Hemoglobin A1c levels which show the average level of blood glucose over the previous 3 months, have been used in the diagnosis and the follow-up of diabetes mellitus. Effect of iron deficiency anemia which is the most common anemia, on hemoglobin A1c levels is...

Aim: Lipid profile is used to determine the risk of cardiovascular diseases (CVD) and to monitor treatment. Reference change value (RCV) represents the clinical significance of the variation between the results of two consecutive tests and laboratory test results exceeding...

Purpose: The measurement of serum ferritin is used as a reliable and noninvasive method for the monitoring of iron stores. There are many different methods for the ferritin measurement. However, the immunoturbidimetric method that having the less cost and possibility of the...

Objective: Comparison of two patient-side glucometers, Accuchek Active (AC) and Optium Xceed (OP)with autoanalyzer Olympus AU 2700 (OL), which uses the reference method.

Materials and Methods: 44 patients, aged over 18, who attended emergency and...

Objective: This study aimed to evaluate the frequency of repeat lipoprotein(a) testing, determine whether repeated measurements changed risk classification, assess the clinical significance of observed changes using the reference change value, and investigate whether the...

Objective: Vitamin B12 has important functions in the body. Its deficiency results in hematological and neurological impairments. Unless the deficiency status treated on early stage this neurological degenerations become permanent. Some studies have shown that the vitamin...

Objective: HDL is considered as anti-atherogenic and it exerts this effect with reverse cholesterol transport and with the contribution of enzymes such as paraoxonase and platelet activating factor acetylhydrolase. Data on biological variation can be used to determine the...

Background: Beta-human chorionic gonadotropin (beta-hCG) is secreted in small amounts by all cells and since the hormone is largely excreted by the kidneys, its levels can be elevated in non-pregnantdialysis patients.

Case presentation: A 27-year-old...

Objectives: This study aims to analyze the turnaround time (TAT) of intraoperative PTH (parathyroid hormone) testing and to support surgical success with objective criteria by calculating reference change values (RCV).

Methods: TAT analysis was...

Objective: Measurement of HbA1c is widely used in patients with diabetes mellitus as a monitor of retrospective glycemic control. Currently, more than 30 different methods are commercially available to measure HbA1c and these methods vary in the fraction of Hb measured and the...

Objective: Urine culture test (UCT), which is the gold-standard for urinary tract infections (UTI), requires higher cost, labour and time than complete urinalysis (CU). Therefore, it is important to assess prediction performance of CU's for UCT. The aim of our study is to...

Purpose: In recent decades, several new techniques for measuring erytrocyte sedimentation rate have been developed in clinical laboratories. The aim of this study to compare three different automated sedimentation analyzers (Micro TEST-1, Sedisystem, Sed Rate Screener) with...

The reference method for the determination of urinary protein excretion in patients with kidney diseases is the measurement of 24-h protein excretion. But 24-h. urine collection is unreliable and cumbersome. So protein/creatinine ratio (P/C) in spot urine is used to determine proteinuria. In this...

Background: The purpose of this study was to investigate the superiority of serum cystatin C levels over serum urea and creatinine in evaluating kidney functions in intensive care unit patients.

Material and Methods: 65 patients in intensive care unit...

Children are quite different from adults not only as structurally, but also their metabolism and in terms of their response to the diseases. The most important variable is the age of the pediatric patients. Clinical biochemist must have knowledgeable about the differences in the interpretation...

This case is presented to emphasize the EDTA-dependent PTP (pseudothrombocytopenia) that should be considered as a possible cause of low platelet count and evaluate the effect of different anticoagulants on complete blood count (CBC). The CBC and blood smears, of the patient who was been...