The official publication of Turkish Society of Clinical Biochemistry
Objectives: Urine specimen determinations sometimes may not be done immediately and may be studied by using urine strips which are ke pt in open air during routine work due to the conditions of study. In this study, the performance characteristics of urine strips and the...
Purpose: Urinary tracts infections (UTI) are the most common cause of bacterial and hospital based infections. The gold standard in the diagnosis of UTI is urine culture. Patients with suspected UTI are usually requested for urinalysis simultaneously with urine culture. In...
Background: It is thought that using a spot urine is more appropriate for microalbuminuria screening than 24 hours timed urine specimens due to collection and standardization difficulties. In this study, we examined the availability of spot urine as a screening test for the...
Aim: To evaluate urine integrity tests performed before illegal and abused substance analysis and to reveal their limitations.
Materials and Methods: This retrospective study was conducted between January 1, 2023 and June 15, 2023, in the AMATEM...
Objective: In our study we aimed to investigate the role of fetuin-A, a systemic calcification inhibitor, and osteopontin, which plays an important role in calcification processes, in the pathogenesis of urinary tract stone disease.
Materials and Methods:...
Objective: It has been reported that glucose intake creates changes at the levels of some electrolytes in serum and urine. The most important change observed in urine is the increase in calcium levels and this is thought to be the result of increased insulin levels in response...
Objective: In this study, we aimed to investigate serum and urine gamma glutamyltransferase (GGT) levels in patients with chronic renal failure (CRF), and also to determine the changes in the different stages of CRF.
Materials and Methods: Serum and...
Objective: IUrinary tract infection (UTI) is a common disease in children. Rapid and reliable diagnosis of UTI is mandatory for the prevention of complications. The aim of the present study was to assess whether or not automated urine analysis can be used as a rapid diagnostic...
Objective: The discrepancy between chemical and microscopic urine examination makes it demanding to interpret the results. We aimed to evaluate the laboratory personnels effect on the consistency between chemical and microscopic urine examination results.
...Aim: Although, urine culture requests to diagnose urinary tract infection (UTI) are very common, about 70-80% of urine samples received in the laboratory are found to be negative. This means increased laboratory workload and cost. Urinary leukocyte esterase and nitrite are...
Objectives: Drug abuse tests are applied to determine drug use to combat disease, crime, or substance abuse. We aimed to investigate whether cheaper and more practical plastic tubes can be an alternative to glass tubes for drug abuse analysis in urine.
Material...
Objective: To evaluate the effect of ascorbic acid on some tests (glucose, blood and leukocyte esterase) by comparing strips that are resistant to its interference and those that measure ascorbic acid.
Material and Methods: We retrospectively...
Aim: Immunofixation electrophoresis (IFE) is a gold standard biochemical technique used in the diagnosis, treatment and follow-up of monoclonal gammopathies. In paraproteinemias, excessive production of immunoglobulins (Ig) known as paraprotein or monoclonal protein...
Objective: N-acetyl-β-D-glucosaminadase (NAG) is a enzyme which exists in the lysosomes of renal proximal tubular cells. Increased NAG activity in urine is accepted as non-invasive early index of tubular damage. Lupus nephritis is known to be the most important complication of...
Objective: The accurate and reliable measurement of addictive substances is a very serious problem all over the world because it involves some legal liabilities. This study aims to measure the popular addictive substances using two common techniques and to reveal against...
Objective: In quantitative analysis of serum proteins turbidimetric and nephelometric methods are the most common. Aim of this study was to compare the nephelometric method with the turbidimetric method for serum and urine samples in our clinical laboratory and to analyse...
Aim: Prostate cancer is the second major cause of cancer-related deaths in men. Digital rectal examination, serum PSA and biopsy are the main tools used in the diagnosis of prostate cancer. The low specificity of PSA leads to unnecessary biopsies. Therefore, biomarkers with...
Objective: Urine culture test (UCT), which is the gold-standard for urinary tract infections (UTI), requires higher cost, labour and time than complete urinalysis (CU). Therefore, it is important to assess prediction performance of CU's for UCT. The aim of our study is to...
Aim: Since glomerular filtration rate (GFR) determined by 24 hours urine is cumbersome, nephrologists recommend using an estimated GFR (eGFR). This study aimed to investigate the agreement between Modification of Diet in Renal Disease (MDRD) and Chronic Kidney Disease...
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