Didem Barlak Keti, Sabahattin Muhtaroğlu
Objective: To evaluate the consistency between total vitamin B12 and holotranscobalamin (holoTC)
measurement results by analyzing holoTC levels in patients with total vitamin B12 deficiency.
Material and Methods: HoloTC level was analyzed by...
Journal of Turkish Clinical Biochemistry
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2021-12-01
Aynur Kırbaş, Medeni Arpa, Medine Cumhur Cüre, Hacer Bilgin Topaloğlu, Ebru Yaprak, Özgür Baykan
Objective: Vitamin B12 has important functions in the body. Its deficiency results in hematological and
neurological impairments. Unless the deficiency status treated on early stage this neurological
degenerations become permanent. Some studies have shown that the vitamin...
Journal of Turkish Clinical Biochemistry
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2016-04-01
Selda Demirtaş, Gökhan Nergizoğlu, Levent Karaca
In chronic renal failure, high plasma homocysteine levels are a common finding and in uremia almost the rule. The cause of hyperhomocysteinemia in ESRD (end stage renal disease) whether it lies in an impared renal or extrarenal metabolism or through uremic retention toxins, is still under...
Journal of Turkish Clinical Biochemistry
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2003-04-01
Arzu Akağaç Etem, Ebru Önalan Etem, Sembol Türkmen Yıldırmak, Mehmet Kırtay
Objective: Vitiligo is an acquired depigmentation disorder occur with destruction of melanocytes, a
common skin disease. We aimed to investigate ferritin, vitamin B12 and folic acid levels in patients with
vitiligo in Usak region.
Material and Methods:...
Journal of Turkish Clinical Biochemistry
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2015-04-01
Yalçın Önder, Sehavet Tezcan, Özlem Hürmeydan Kadılar, Lale Köroğlu Dağdelen, Özlem Çakır Madenci, Nihal Yücel, Asuman Orçun
Purpose: The purpose of this study is to determine serum B12 and folic acid reference values that can
be used in our hospital district population.
Materials and Methods: 300 healthy individuals were chosen according to CLSI Approved Guideline
C28-A....
Journal of Turkish Clinical Biochemistry
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2014-12-01
Sabriye Özkaya Kafesçiler, Mine Mishakioğlu, Cengiz Ceylan, Ertan Özdemir, Tamer Şanlıdağ
Objective: Elevated levels of serum beta-2 microglobulin can be expected in megaloblastic anemias due to defective DNA sythesis, increased ineffective eryhropoesis and increased cell turnover.
Materials and Methods: 64 cases of megaoloblastic anemia due...
Journal of Turkish Clinical Biochemistry
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2004-08-01
Ceyda Kabaroğlu, Kenan Aksu, Gökhan Keser, Fahrettin Oksel, Işıl Mutaf, Sara Habif
Aim: Raynaud's phenomenon is characterized by transient reduction in blood supply through the small arteries in the hands and feet. Secondary Raynaud's phenomenon accompanies collagen vascular diseases such as rheumatoid arthritis and scleroderma. The relationship between...
Journal of Turkish Clinical Biochemistry
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2004-04-01
Serap Cuhadar, Ayşenur Atay, Mehmet Köseoğlu
Objective: It is unclear whether there is a relationship between lithium administration and folate and vitamin B12metab olism.
Materials and Methods: We compared retrospectively serum B12, and serum folate concentrations in
patients receiving and not...
Journal of Turkish Clinical Biochemistry
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2010-08-01
Selen Şen, Gülgün Durat, Işık Atasoy
The vitamin B12and folic acid are water soluble vitamins the metabolisms of which are connected to
each other and which are necessary for various metabolic paths in the central nervous system. These
vitamins are used as cofactors in the conversion of the homocysteine, the high concentrations of...
Journal of Turkish Clinical Biochemistry
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2009-04-01
Özgür Baykan, Sema Bülte
Objective: Increasing the role of laboratories in the diagnosis processes is associated with a growing
number of the requested laboratory tests. However, this situation is considered as time consuming and
also accompanied by an increase in costs, as well as additional...
Journal of Turkish Clinical Biochemistry
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2018-04-01