This case highlights the effect of heterophilic antibody interference in two siblings with hypopituitarism. Prolactin measurements performed on the UniCel DxI 800 in patients followed up with a diagnosis of hypopituitarism were found to be falsely elevated. For further investigation, polyethylene...

Background: Cold agglutinin disease is a rare autoimmune hemolytic disease causing the agglutination of erythrocytes by the activation of antibodies at low temperatures. Cold agglutinin disease should be kept in mind in terms of getting the right diagnosis and treatment...

Objectives: The carbohydrate antigen 19-9 assay is a widely used biomarker as a complement to other tests in the detection and follow-up of pancreatic, bile duct and colon cancer in high-risk individuals. The CA 19-9 assays often give different results with different...

Background: Cold agglutinin disease; is a rare autoimmune hemolytic anemia caused by IgM antibodies (rarely IgA or IgG) against polysaccharide antigens on erythrocytes at low temperatures. As the cold activated antibodies cause degeneration and autoagglutination in the...

Objective: Graves' disease is an autoimmune disease which results in excessive production of thyroid hormones and is the most common cause of hyperthyroidism. TRAb has a key role to confirm the clinical diagnosis of Graves' disease. The different measurement methods have...

D-dimer antigen is a fibrin degradation product that is formed by the sequential action of three different enzymes on cross-linked fibrin. As such, increased levels of plasma D-dimer should be reliable indicator of thrombus formation. The D-dimer antigen is a specific marker of fibrin clot...

Objective: The objective of this study was to evaluate of accuracy of the immuno-turbidimetric method.

Material and Methods: Patients (n=160) were tested with the D-Dimer assay with a STalia®D-DI (D-dimer) (Diagnostica Stago, Asnieres, France). D-dimer...

Screening for fecal occult blood has been shown to be effective in reducing the colorectal cancer mortality. Guaiac-based tests are one of the most frequently used screening tests, but their false positivity and negativity rates are quite high. Peroxidase enzyme, found in many fruits and...

Objective: Confirmation of the clonality of B lymphocytes by flow cytometry analysis has an important role in the diagnosis of Chronic Lymphocytic Leukemia (CLL). In this retrospective study, we investigated which surface light chain pattern they showed as indicative of the...