Aim: The aim of this study was to extensively evaluate four fully-automated photometric methods directly measuring antioxidant capacity; ferric ion reducing power, total antioxidant status, total antioxidant response, total thiol and to reveal the weak and strong sides of...

Aim: To evaluate the relationship between serum oxidant-antioxidant levels and the duration of the illness, disease activity and treatment modality in patients with axial spondyloarthritis (axSpA).

Material and Methods: Fourty two patients with axSpA...

Objective: We aimed to determine the relationship between some oxidative and antioxidant parameters and cancer status. Therefore, the activity of serum PON1, an enzyme known as a lipid antioxidant, as well as serum level of TBARS, the end product of lipid peroxidation, and...

Aim: During iron deficiency anemia (IDA), increased oxidative stress is accompanied by reduction in antioxidant defense systems and increased lipid peroxidation. We aimed to assess oxidative balance and Deoxyribonucleic Acid (DNA) damage in reproductive-aged women with...

Diabetes mellitus is a metabolic disease characterized by hyperglycemia resulting from defective insulin secretion or resistance to insulin action, or both. Production of sugar alcoholes called as metabolic hypothesis, ischemia-hipoxia oxidative stress, and insufficiency of neurotrophin or...

Objective: It has been demonstrated that oxidative stress induced tissue damage plays a role in the pathogenesis of several otolaryngological diseases. The aim of the present study was to evaluate the selenium (Se), zinc (Zn) and copper (Cu) levels in the plasma of children...

Objective: The oxidative stress and renal vasoconstriction are considered to have an effect on the pathophysiology of contrast induced nephropathy. In this study, we aimed to evaluate the effects of contrast agents on serum creatinine, total antioxidant capacity and estimated...

Objective(s):Unexplained infertility (UI) is a multifaceted reproductive disorder with an ambiguous cause. Oxidative stress has arisen as a possible factor in its pathophysiology. This study sought to evaluate the significance of the equilibrium between oxidative and antioxidant levels, alongside...

Objective: The aim of the study was to investigate the relationship between viral load and lipid peroxidation and antioxidant enzymes in patients with hepatitis B virus (HBV) infection.

Materials and Methods: We examined 50 patients (26 male, 24 female)...

Objective: Defibrotide, a polydeoxyribonucleotide, has been found to modulate endothelial cell function and to have an antithrombotic effect on arteries, veins and capillaries. A significant amonut of evidence has been found about the protective role of defibrotide in...

Objective: Portal hypertension is a hyperdinamic circulation disorder characterized by high portal venous pressure. The aim of the study is to reveal oxidative damage measuring nitric oxide levels and myeloperoxidase, xanthine oxidase, superoxide dismutase and glutathione...

Objective: Nicotine is an important component of cigarette smoke. Nicotine administration may result in oxidative stress by inducing the generation of reactive oxygen species in the periphery and central nervous system. Numerous epidemiological studies have demonstrated an...

Objective: Reduced glutathione is the most important antioxidant molecule of intracellular medium and a good marker for investigating antioxidant defence mechanism in diseases which are caused by oxidative stress. In this study we compared the spectrophotometric measurement...

Purpose: To investigate the effects of melatonin on serum paraoxonase and lactonase activities in isoproterenol-induced myocardial infarction.

Materials and Methods: Rats were divided into four groups as control, melatonin, ISO and ISO+melatonin....

It has been reported that oxidative stress is increased in diabetes mellitus and the increase in oxidative stress gives rise to complications of this disease. In the present study, we aimed to investigate the effects of vitamin A, E, and C treatments combined with insulin on the oxidative and...

Aim: The oxidative stress which is caused by free radicals can play role in emerging and/or progressing many diseases. Hyperthyroidism can induce a lot of changes dealing with the systems of nitric oxide (NO) and antioxidant systems of several tissues in increasing the...

Objective: Stroke, in all over the world, the one of the leading causes of morbidity and mortality especially in the geriatric population. Oxidative stress has an important role in pathophysiology of ischemic stroke. Malondialdehyde (MDA) is an important parameter of...

Objective: The aim of this study was to evaluate the effects of nicotine on myocardium of newborn rats whose mothers received nicotine during gestation and lactation, by using biochemical and pathological parameters and to evaluate the role of antioxidant enzymes, free oxygen...

Dietary cholesterol is suggested to cause atherosclerosis and to increase the production of free radicals. It is reported that hypercholesterolemic diet may make some changes on the antioxidant system. In our study, we aimed to observe the effect of N-acetylcysteine (NAC) treatment on the...

Endometriosis is frequently associated with infertility and spontaneous abortus. Studies which had been carried on the subjects with endometriosis revealed the abnormal expression of the antioxidant defense enzymes, and suggested an inbalance in free radical metabolism. This study was designed to...

Objective: Serum paraoxonase (PON1) is a HDL associated esterase and inhibits LDL oxidation. The oxidative modification of LDL plays an important role in the pathogenesis of atherosclerosis. In hemodialysis patients, the increased oxidative stress induces oxidative...

Objective: It has been reported that liver oxidative stress increases in streptozotocin induced experimental diabetes. The aim of this study is to investigate the effects of L-carnitine possessing antioxidant activity on liver protein oxidation seen in diabetes.

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Purpose: Obstructive jaundice leads to hepatic injury and fibrosis. Icterus causes immunologic depression resulting in bacterial translocation. In this study, we aimed to investigate the effects of vitamin E and L-arginine supplementation on glutathione systems and bacterial...

Objective: In this study, we aimed to evaluate the possible effects of leptin and oxidative stress on the pathogenesis of type 1 and type 2 diabetes mellitus.

Material and Methods: Subjects were assigned to four groups: type 1 diabetes group (n=20),...

Purpose: Activation of the renin-angiotensin system leads to an increase in oxidative stress. We investigated erythrocyte antioxidant enzymes, glutathione peroxidase, glutathione reductase and glutathione-S-transferase activities and as an index for oxidative stress plasma...