Objective(s):Unexplained infertility (UI) is a multifaceted reproductive disorder with an ambiguous cause. Oxidative stress has arisen as a possible factor in its pathophysiology. This study sought to evaluate the significance of the equilibrium between oxidative and antioxidant levels, alongside...

Aim: The evaluation of biomarkers linked with inhibition and activation of vascular calcification in pre and post renal transplant period in renal transplant recipients was aimed in this research.Patients and

Methods: 35 recipients who had undergone...

Objective: Obesity represents a significant global health concern characterized by substantial metabolic abnormalities and a heightened risk of developing type 2 diabetes mellitus (T2DM). Novel peptides including irisin, adropin, and preptin have been shown to play important...

Ovarian cancer has often been described as a “silent killer,” but recent studies have shown that there are symptoms that appear in the early stages of the disease. Recognition of these symptoms is critical because early diagnosis improves the probability of cure. Use of serum biomarkers for the...

Purpose: Although most studies showed that the increase of cardiac biomarkers due to myocardial injury during coronavirus disease (COVID-19) is a strong predictor of adverse clinical events, few studies compared other causes of myocardial injury and COVID-19. In our study,...

Aim: Prostate cancer is the second major cause of cancer-related deaths in men. Digital rectal examination, serum PSA and biopsy are the main tools used in the diagnosis of prostate cancer. The low specificity of PSA leads to unnecessary biopsies. Therefore, biomarkers with...

Aim: Early risk classification after acute myocardial infarction is very important for the prediction of complications. In this study, it was aimed to find the most sensitive panel in the prediction of prognosis after acute myocardial infarction by multi-biomarker...

Neutrophil gelatinase-associated lipocalin (NGAL), is a small, robust protein expressed by neutrophils and various epithelia, including the renal proximal tubules. While initially proposed as a marker for infections and certain adenocarcinomas, it is now apparent that its early and dramatic rise...

Objective: Since the emergence of Coronavirus Disease 2019 (Covid-19) in December 2019, it has turned into a pandemic. Covid-19 infection; can trigger pulmonary inflammation and also cause acute lung injury. In cases with severe pneumonia, long hospital stays and high...

Introduction: The disease caused by SARS-CoV-2, which the World Health Organization has considered as a pandemic, was named COVID-19 and has since spread worldwide. The COVID-19 pandemic has drastically changed the way we live and work. During events like COVID-19, it is...

Aim: The measurement uncertainty (MU) of high-sensitivity troponin T (hs-TnT) and myoglobin assays was calculated in accordance with ISO/TS 20914:2019. The calculated MU values were subsequently compared with the relevant analytical performance specifications (APS).

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Purpose: End-stage renal disease; is a disease characterized by loss of renal function where inflammation is involved in its pathogenesis. Adiponectin is an anti-inflammatory protein secreted from the adipose tissue. ICAM-1 and VCAM-1 are vascular adhesion molecules that...

Aim: Many mediators and biomarkers play a role in the pathogenesis of bacterial sepsis (BS) which is still not fully illimunated.The aim was to analyze intracellular oxidised glutathione (GSSG)/reduced glutathione (GSH) and serum thiol/disulfide (extracellular) homeostasis...

Amyotrophic lateral sclerosis (ALS) is a fatal disorder of motor neuron degeneration with unclear etiology and no effective treatment to date. The cause of the most cases of ALS remains unknown. Research in ALS has been stimulated by a series of genetic and molecular pathology discoveries. ALS...

Aim: Many mediators and biomarkers play a role in the pathogenesis of bacterial sepsis (BS) which is still not fully illimunated. The aim was to analyze intracellular oxidised glutathione (GSSG)/reduced glutathione (GSH) and serum thiol/disulfide (extracellular) homeostasis...

Aim: Pancreatic cancer (PC) is a disease with complex and poorly understood etiology. One of the common risk factors of PC is diabetes mellitus (DM). Increased carbohydrate antigen (CA) 19-9 levels can be used as a biomarker in diagnosis of PC. However, CA 19-9 levels have...

Objective: In recent years hsCRP and procalcitonin has started to be used in diagnosis and assessment of the prognosis of cardiovascular diseases. In this study we aimed to evaluate the prognostic significance of alterations in C-reactive protein (CRP) and procalcitonin...

Objective: ST-segment elevation myocardial infarction (STEMI) is an important cause of morbidity and mortality. Platelet (PLT) activation and thrombosis have important roles in the process of atherosclerosis that is one of the most important cause of acute ischaemic...

Traumatic Brain Injury (TBI) is described as the brain damage occured by direct and indirect forces. Although TBI is a common health care problem, its diagnosis, management and the prediction of prognosis still remain obscure.S100B, neuron specific enolase (NSE), Glial fibrillary acidic protein...

Vitamin D is a molecule, now seen as a hormone, it plays an important role in bone health, it is also associated with many diseases, such as diabetes, cancer and cardiovascular problems. 25- hydroxyvitamin D [25(OH)D] is used to estimate vitamin D status because its long half-life. However, to...