The official publication of Turkish Society of Clinical Biochemistry
Objective: Obesity promotes the development of diseases in many organ systems. The relationship between lipoporotein (a), lipid parameters and insulin resistance which accompany obesity has not been clarified. The correction of dyslipidemia in obesity and insulin resistance is...
Objective: The aim of the present study is to investigate the relation between new obesity indices waist circumference/height (WtHR), visceral adiposity index (VAI) and body adiposity index (BAI) and homeostasis model assessment of insülin resistance (HOMA-IR) index and...
Aim: Leptin is a nonglycolyzed peptide, made of 146amino-acids, that is produced by ob-gene in fat tissue. Leptin in circulation shows its effects by inhibiting Neuropeptide-Y in central nervous system and shows its effects on body fat mass by decreasing appetite and...
Objectives: It has been suggested that adhesion molecules may contribute to the pathogenesis of numeruos diseases as mediators of inflammatory process by cell to cell interactions. The aim of the present study was to evaluate serum levels of soluble intercellular adhesion...
Objective: Adiponectin, is a novel adipose tissue specific protein that has structural homology collagen VIII, X and complement factor C1q. It is also shown that insulin resistance and obesity cause to diminish adiponectin extraction from human adipose tissue but the...
Objective: Obesity is the leading public health problem in this century. In this study we aimed to evaluate the hsCRP levels which are the indicators of inflammation in obese people (defined with BMI) and assess the relation between obesity and hsCRP.
Materials...
Aim: Polycystic ovarian syndrome (PCOS) is a multifactorial disorder with different phenotypic characteristics, the most frequent endocrine disorder in women, and the leading cause of anovulatory infertility. Kisspeptin is recognized to have a crucial function in regulating...
Aim: During iron deficiency anemia (IDA), increased oxidative stress is accompanied by reduction in antioxidant defense systems and increased lipid peroxidation. We aimed to assess oxidative balance and Deoxyribonucleic Acid (DNA) damage in reproductive-aged women with...
Objective: Various algorithms for predicting coronary atherosclerosis have been established, most of which are based on large epidemiologic and cohort studies. We examined the predictive value of various clinical and biochem ical markers for angiographically defined coronary...
Objective: Recently It's thought that Vitamin D deficiency not only adversely affects musculoskeletal system but also many other systems in our body. Since operating room staff exposed to sunlight lesser than the majority of population, we tried to show Vitamin D status of...
Objective: The discovery of vitamin D receptors and vitamin D activating enzymes in several cells other than those involved in bone and mineral metabolism brought the non-classical effects of vitamin D into focus. It was reported that diabetic patients have significantly...
Aim: To investigate the presence of oxidative stress and dyslipidemia, which increase cardiovascular risk, and the effect of gonadotropin replacement therapy on these parameters in patients with Idiopathic Hypogonadotropic Hypogonadism (IHH).
Material and...
Aim: The aim of this study is to investigate the possible effects of chronic smoking on serum vitamin D and some inflammation markers.
Materials and Methods: The smoking history of a total of 110 volunteer adults, 76 females and 34 males, for whom 25...
Objective: In this study, we investigated the relationship between androgen levels and type 2 diabetes in men and women.
Material and Methods: 99 diabetic patients receiving oral antidiabetic treatment, without any micro and macrovascular complications,...
Aim: Smoking is accepted as a risk factor for primary chronic diseases such as cardiovascular diseases and respiratory system diseases and for cancer development. The aim of this study was to indicate the increase in inflammation in smokers by using high-sensitivity...
Objective: The aim of this study is to determine the correlation between insulin resistance and serum IL-8 levels of obese individuals with normal glucose tolerance.
Materials and Methods: 72 obese individuals with the ages ranging from 20 to 59 and...
Objective: In this study, we aimed to evaulate serum C-reactive protein (CRP), interleukin 6 (IL-6), and neopterin levels with lipoprotein phospholipase A2(Lp-PLA2) activity in obese adolescents with or without insulin resistance, and to demonstrate their relationships with...
Fully Diamond OA with no APCs and no submission fees. Your research is freely available to readers worldwide from the day it publishes.
Double-blind peer review from an active editorial team returns a first decision in about 30 days, keeping your manuscript moving.
Backed by the Turkish Society of Clinical Biochemistry, JTCB welcomes submissions from researchers worldwide and reaches an international laboratory audience.
Method validation, analyzer comparisons, reference intervals, quality indicators, preanalytical studies, and instructive clinical case reports.
All manuscripts publish in English and follow ICMJE and COPE guidelines, with Crossref DOIs and TR Dizin indexing ensuring global discoverability.