Büşra Akşit Koldaş, Tevfik Noyan
Aim: The aim of this study was (1) to compare the serum insulin, ghrelin, obestatin and, copeptin levels
between pregnant and non-pregnant women and (2) investigate the changes in these parameters in
pregnant women that measured at before and second hour after 75 gram (g)...
Journal of Turkish Clinical Biochemistry
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2021-04-01
Rabia Nur Kocabaş, A. Erkin Bozdemir, Güneş Başol, Burcu Barutçuoğlu, Zuhal Parıldar, Ceyda Kabaroğlu, Oya Bayındır
Objective: Cardiovascular diseases (CVD) are the leading causes of death worldwide. After understanding the importance of inflammation in the pathogenesis, CRP usage has been increased for the determination of cardiovascular risk. As an inflammation marker, the relationship...
Journal of Turkish Clinical Biochemistry
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2007-08-01
Emin Savaş Kılavuz, Mehmet Tosun, Tuba Şanlı, Nermin Erol
Objective: The aim of this study is to research relations between first hour glucose and insuline level and inflamation markers in individuals who was loaded 75 grams glucose.
Materials and Methods: 11 individuals who were non obese and normal glucose...
Journal of Turkish Clinical Biochemistry
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2011-04-01
Giray Bozkaya, Emrah Özgü, Baysal Karaca, Onur Özgenç
Objective: Mean platelet volume (MPV) is a determinant of platelet function. Determining the MPV
levels is very important for the diabetic patients who have the risk of developing vascular diseases.
The aim of this study is to investigate any significant difference in the...
Journal of Turkish Clinical Biochemistry
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2008-04-01
Giray Bozkaya, Ayşen Lale, Tuba Orhan, Baysal Karaca
Objective: It has been reported that glucose intake creates changes at the levels of some electrolytes in serum and urine. The most important change observed in urine is the increase in calcium levels and this is thought to be the result of increased insulin levels in response...
Journal of Turkish Clinical Biochemistry
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2005-12-01
Evin Kocatürk, Alparslan Birdane, Arif Alper Cevik, Ertugrul Colak, Ahmet Musmul, Omer Colak
Aim: Early risk classification after acute myocardial infarction is very important for the prediction of
complications. In this study, it was aimed to find the most sensitive panel in the prediction of prognosis
after acute myocardial infarction by multi-biomarker...
Journal of Turkish Clinical Biochemistry
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2022-12-01
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DOI: 10.56615/tkbd.2022.14
Gülsüm Feyza Altaş, Sezer Uysal
Objective: The use of glycemic markers in the follow-up of Diabetes Mellitus is important to prevent the
development of complications. Glycated hemoglobin (HbA1c) is more stable and exhibits glucose status
of 8-12 weeks, while fasting plasma glucose (APG) reflects the...
Journal of Turkish Clinical Biochemistry
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2017-08-01
Çiğdem Sönmez, Şenay Arıkan, Yüksel Koca, Şemnur Büyükaşık, Yahya Büyükaşık, Turan Turhan
Aim: Leptin is a nonglycolyzed peptide, made of 146amino-acids, that is produced by ob-gene in fat
tissue. Leptin in circulation shows its effects by inhibiting Neuropeptide-Y in central nervous system and
shows its effects on body fat mass by decreasing appetite and...
Journal of Turkish Clinical Biochemistry
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2020-08-01
Hülya Yalçin, Burak Toprak, Ayfer Çolak, Aybike Hastürk Günaslan
Objective: The discovery of vitamin D receptors and vitamin D activating enzymes in several cells other
than those involved in bone and mineral metabolism brought the non-classical effects of vitamin D into
focus. It was reported that diabetic patients have significantly...
Journal of Turkish Clinical Biochemistry
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2017-08-01
Şerif Ercan, Mahmut Çakır
Objective: The use of different types of analyzers and samples lead to obtaining different test results.
This study aimed to investigate whether the test results yielded by conventional blood gas analyzer
(cBGA) are considered interchangeable with those produced by...
Journal of Turkish Clinical Biochemistry
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2018-04-01
Özlem Gülbahar, Ayşe Banu Çaycı, İrem Budakoğlu, Uğur Erçin, Neslihan Bukan, Hatice Paşaoğlu, Tuncay Nas
Objective: Gestational diabetes mellitus is one of the most frequent complications in pregnancy which may create a health risk for the mother and the child. Different criteria may be used in the diagnosis of gestational diabetes mellitus. In the present study we aimed to test...
Journal of Turkish Clinical Biochemistry
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2010-08-01
Inanc Karakoyun, Fatma Demet Arslan
Aim: Pancreatic cancer (PC) is a disease with complex and poorly understood etiology. One of the
common risk factors of PC is diabetes mellitus (DM). Increased carbohydrate antigen (CA) 19-9 levels
can be used as a biomarker in diagnosis of PC. However, CA 19-9 levels have...
Journal of Turkish Clinical Biochemistry
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2020-12-01
F. Demet Arslan İnce, Banu Arslan Şentürk, Serkan Kap, Evren Akgöl, Füsun Üstüner
Objective: Uncertainty is a parameter that characterize a range which includes a measurable substantiality. It also shows how much the result represents the real value. Uncertainty of measurement comprises many components. The purpose of this study was to estimate uncertainty...
Journal of Turkish Clinical Biochemistry
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2007-04-01
Esra Ekiz, Şermin Acar Duran, Mihriban Ulaş
Objective: Comparison of two patient-side glucometers, Accuchek Active (AC) and Optium Xceed
(OP)with autoanalyzer Olympus AU 2700 (OL), which uses the reference method.
Materials and Methods: 44 patients, aged over 18, who attended emergency and...
Journal of Turkish Clinical Biochemistry
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2014-04-01
Tevfik Noyan, Murat Cihan, Esra Yiğit, Fatih Ahmet Uzdu
Objective: The aim of this study was to retrospectively evaluate the performance of 2 glucometer devices using the accuracy criteria specified in ISO 15197:2015.
Methods: Glucose results obtained from Accu-Chek Inform II and Sejoy BG-707 glucometers,...
Journal of Turkish Clinical Biochemistry
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2026-08-25
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DOI: 10.65717/jtcb.2026.26027
Dilek İren Emekli, Kenan Güçlü, Gamze Turna, Bilal İlanbey, Rukiye Nar, Esin Avcı Çiçek
Objective: Analytical reliability of clinical laboratories may be obtained by internal quality control,
external quality control by analyzing the data with statistical methods. In Six Sigma Methodology, which
is one of these methods, the analytical performance of the tests...
Journal of Turkish Clinical Biochemistry
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2016-08-01
Belkız Öngen İpek, Mustafa Erinç Sitar
Objective: For this current study, our aims were to investigate the relationships between HbA1c with
neutrophil lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR) which are accepted as new
markers of systemic inflammation and the relationships between HbA1c with CRP...
Journal of Turkish Clinical Biochemistry
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2018-08-01
Giray Bozkaya, Murat Örmen
Purpose: Hemoglobin A1c (HbA1c), also known as glycated hemoglobin, indicates the blood glucose
control over the last 8-12 weeks. HbA1c level is a useful marker for the monitoring of the diabetic
patient and shows the necessity of any adjustment to the treatment has to be...
Journal of Turkish Clinical Biochemistry
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2018-08-01
Aram Aslan, Gökçe Aktaş, Ömer Emecen, Hale Aral, Murat Usta, Berrin Berçik İnal, Pınar Tonbaklar Bilgi, Güvenç Güvenen
Objective: At Emergency Department, we aimed to compare the test results of serum samples
obtained from the tubes containing thrombin to take short span of time for clotting (RST) with the
tubes containing serum separator gel with clot activator (SST II Advance) that we have...
Journal of Turkish Clinical Biochemistry
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2008-04-01
B.A. Şentürk, F. Üstüner, S. Aksu, Z. Sülek
Objective: Plasminogen activator inhibitor type I (PAI-1) an inhibitor of fibrinolysis and an important and independent cardiovascular risk factor, has been shown to be elevated in obesity. The aim of this study was to evaluate plasma PAI-1 levels in obese subjects and to...
Journal of Turkish Clinical Biochemistry
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2005-12-01
Çiğdem Karakükcü, Meral Mert, Ahmet Karaman
Objective: There is an increase in platelet activation in diabetics and patients with diabetic
complications. Labile hemoglobin A1c (LHbA1c), an early glycation product, can turn into other
glucose metabolites which can be responsible for many kinds of pathologies observed...
Journal of Turkish Clinical Biochemistry
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2011-12-01
Barış Sağlam, Sezer Uysal, Banu Önvural
Diabetes Mellitus (DM) is a very common chronical disease of our country. In diagnosis of DM and
monitoring of glycemic values, besides glucose,HbA1c is also being used. However HbA1c cannot reflect
glycemic levels for short term and also, conditions like anemia, hemoglobinopathies and chronic...
Journal of Turkish Clinical Biochemistry
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2014-08-01
Ahmet Çelik, Gürkan Çıkım, Edibe Sarıçiçek, Elif Şahin, Metin Kılınç
Objective: The aim of the present study is to investigate the relation between new obesity indices waist
circumference/height (WtHR), visceral adiposity index (VAI) and body adiposity index (BAI) and
homeostasis model assessment of insülin resistance (HOMA-IR) index and...
Journal of Turkish Clinical Biochemistry
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2014-04-01
Asuman Orçun, İnci Küçükercan, Özlem Çakır Madenci, Nuray Kolcu, Buket Tekçe
Early diagnosis and efficient therapy is essential for the prevention of micro and macrovascular complications of diabetes mellitus (DM). Different diagnostic criteria for DM have been proposed by different international organizations. In this study we compared criteia of "National Diabetes Data...
Journal of Turkish Clinical Biochemistry
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2003-08-01
Sibel Bilgili, Özge Fenercioğlu, Gizem Ercan, Giray Bozkaya
Purpose: Oral glucose tolerance test (OGTT) is a very important procedure in diagnosing diabetes
mellitus. It is very crucial to perform OGTT according to the rules that must be taken into account in
preparation period of the test. Our aim was to determine the level of...
Journal of Turkish Clinical Biochemistry
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2021-08-01