Raziye Yıldız
Aim: Hemolyzed specimens are often a significant cause of economic and clinical problems between
the clinics and the laboratory. The rate of hemolysis is markedly higher in the Emergency Department
(ED) as compared with other hospital departments. We aimed to reduce the rate...
Journal of Turkish Clinical Biochemistry
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2021-04-01
Giray Bozkaya, Murat Örmen, Özge Esenlik
Purpose: Hemolysis is one of the most important preanalytical factors affecting the laboratory test
results. It is mostly seen in blood samples sent from the emergency department compared to all
samples accepted to the laboratory. If hemolysis is present, the tests affected...
Journal of Turkish Clinical Biochemistry
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2016-12-01
Bilal İlanbey, Kenan Güçlü
Aim: Measurement of cardiac troponins is of great importance in the diagnosis and follow-up of acute
myocardial infarction. The diagnostic specificity of myocardial infarction has increased with algorithms
including serial troponin measurements. It is important that the...
Journal of Turkish Clinical Biochemistry
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2021-08-01
Nuri Orhan, Hayriye Ak Yıldırım, Hatice Yüksel, Özlem Yavuz, Ramazan Memişoğullar
Objective: The cardiac troponins are sensitive and specific biochemical markers of myocardial
damage. It has been suggested that hemolysis causes interference in the immunometric cardiac
troponin assay. The current study aimed to determine the significance of hemolysis as an...
Journal of Turkish Clinical Biochemistry
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2010-04-01
Türkan Yiğitbaşı, Banu Aslan Şentürk, Yasemin Baskın, Mutlu Öney, Füsun Üstüner
Objective: Although there have been many studies about the pre-analytic errors of hemolysis on laboratory tests, different results were found with different work environments and different methods. This study was put together to investigate the effects of hemolysis on routine...
Journal of Turkish Clinical Biochemistry
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2010-12-01
Erdem Çokluk, Fatıma Betül Tuncer, M. Ramazan Şekeroğlu, Selin Tunalı Çokluk
Aim: The aim of the study was to evaluate the sample rejections reasons by the quality indicators and
six sigma process, to determine the acceptability of the rejection reasons and to improve them during
the follow-up process.
Material and Method: The...
Journal of Turkish Clinical Biochemistry
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2020-04-01
Arzu Kösem, Canan Toğçuoğlu, Sevilay Sezer, Turan Turhan
Purpose: A parameter associated with the result of a measurement that characterises the dispersion of
the values that could reasonably be attributed to the measurand is defined as measurement uncertainty
(U). Measurement uncertainty is very important for the clinician to...
Journal of Turkish Clinical Biochemistry
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2021-04-01
Aysun Coşkun, Hale Aral, Güvenç Güvenen, Mustafa Gültepe
Objective: The present study examines the effect of hemolysis on serum sodium concentrations in hyponatremic and hypernatremic serum samples.
Material and Methods: Samples were assessed by three different sodium methods; direct ISE by means of dry...
Journal of Turkish Clinical Biochemistry
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2005-04-01
Merve Ergin Tuncay
Aim: The aim of this study was to extensively evaluate four fully-automated photometric methods
directly measuring antioxidant capacity; ferric ion reducing power, total antioxidant status, total
antioxidant response, total thiol and to reveal the weak and strong sides of...
Journal of Turkish Clinical Biochemistry
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2019-12-01
Gizem İnal, Abdullah Arpacı
Sickle cell disease is a blood disorder that affects erythrocytes one of the most common single gene
disorders in the world and the incidence is high in Turkey. Mutation in the beta globin gene leads to the
formation of sickle hemoglobin tetramers. These tetramers polymerize and damage the...
Journal of Turkish Clinical Biochemistry
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2021-04-01
Tuncay Küme, Ali Rıza Şişman, Aygül Özkaya, Canan Çoker
Objective: To determine the preanalytical errors in specimens sent from the emergency department
to the laboratory and to evaluate the causes and the consequences.
Material and Methods: All the specimens sent from the emergency department were...
Journal of Turkish Clinical Biochemistry
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2009-08-01
Cemal Kazezoğlu, Yasemin Tuğba Sutaşır
Objectives: With the Department of Laboratory Services of the Ministry of Health entering into force
with the general rule no. 2017/12, corrective actions were taken in the preanalytical, analytical and
postanalytical processes related to the regulation of ethanol in the...
Journal of Turkish Clinical Biochemistry
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2019-04-01
Aram Aslan, Gökçe Aktaş, Ömer Emecen, Hale Aral, Murat Usta, Berrin Berçik İnal, Pınar Tonbaklar Bilgi, Güvenç Güvenen
Objective: At Emergency Department, we aimed to compare the test results of serum samples
obtained from the tubes containing thrombin to take short span of time for clotting (RST) with the
tubes containing serum separator gel with clot activator (SST II Advance) that we have...
Journal of Turkish Clinical Biochemistry
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2008-04-01
Hasan Arıcı
Purpose: It is critical to detect the errors in the preanalytical phases and reject the unsuitable samples
for the patient safety and treatments. In this study, it is aimed to determine the situations where the
samples reasons of rejectionare needed to be examined, developed...
Journal of Turkish Clinical Biochemistry
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2021-04-01
Sibel Kulaksızoğlu, Hamit Yaşar Ellidağ, Esin Eren, Necat Yılmaz
Background: Cold agglutinin disease is a rare autoimmune hemolytic disease causing the
agglutination of erythrocytes by the activation of antibodies at low temperatures. Cold agglutinin
disease should be kept in mind in terms of getting the right diagnosis and treatment...
Journal of Turkish Clinical Biochemistry
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2015-08-01
Dilara Karacan, Özlem Gürsoy Doruk, Yavuz Doğan, Pınar Tuncel
Purpose: A parameter associated with the result of a measurement that characterises the dispersion of
the values that could reasonably be attributed to the measurand is defined as measurement uncertainty
(U). Measurement uncertainty is very important for the clinician to...
Journal of Turkish Clinical Biochemistry
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2020-08-01
Tevfik Noyan, Abdullah Üner, Sevim Eşmedere Eren, Murat Cihan
Aim: In this study, it was aimed to evaluate the preanalytical process performance in our laboratory with
the six-sigma methodology and to investigate the effect of the training given to the hospital staff on the
sigma values.
Materials and Methods:...
Journal of Turkish Clinical Biochemistry
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2022-04-01
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DOI: 10.56615/tkbd.2022.08
Yeşim Güvenç
Purpose: Rejection of unsuitable samples is important for the quality of the laboratory results. In our
study, it is aimed to perform sample rejection analysis of blood samples from outpatient, inpatient and
emergency units and to evaluate the effectiveness of the training...
Journal of Turkish Clinical Biochemistry
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2017-12-01
Sebahat Özdem, S. Halide Akbaş, Meral Gültekin
Objective: Therapeutic drug monitoring for lithium therapy is important because of its narrow therapeutic range and non-specific nature of clinical findings of lithium toxicity. Methods such as ion-specific electrode (ISE), atomic absorption and flame emission have been used...
Journal of Turkish Clinical Biochemistry
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2006-12-01