Türkan Yiğitbaşı, Serkan Kap, Yasemin Baskın, Banu Aslan Şentürk, Nihal Kahya Eren, Füsun Üstüner, Oktay Ergene
Objective: Levels of C-reactive protein might be important, in coronary artery disease regarding
long-term risk assessment and prognosis. It has been showed that coronary artery disease is
associated with high levels of C-reactive protein whereas the relationship between...
Journal of Turkish Clinical Biochemistry
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2009-04-01
Gökhan Utku, Sembol Türkmen Yıldırmak, Müberra Vardar, Ekrem Özakın, Yüksel Gülen Özbanazı, Veli Mihmanlı, Hatice Birgül Ayabakan, Hülya Çerçi
Objective: Pre-eclampsia is a pregnancy specific form of hypertension and a multisystem disorder of maternal and placental origin. Pregnancy associated plasma protein-A (PAPP-A) is a insulin like growth factor binding protein 4- degrading metalloproteinase. The aim of this...
Journal of Turkish Clinical Biochemistry
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2013-08-01
Ali Rıza Şişman, Tuncay Küme, Pınar Akan, Pınar Tuncel
The use of C-reactive protein (CRP) analyses in different fields of clinical practice is increasing each day. In particular, investigations indicating the potency of C-reactive protein as a marker in predicting future coronary heart disease and cerebrovascular disease in healthy people are...
Journal of Turkish Clinical Biochemistry
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2007-04-01
Emin Savaş Kılavuz, Mehmet Tosun, Tuba Şanlı, Nermin Erol
Objective: The aim of this study is to research relations between first hour glucose and insuline level and inflamation markers in individuals who was loaded 75 grams glucose.
Materials and Methods: 11 individuals who were non obese and normal glucose...
Journal of Turkish Clinical Biochemistry
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2011-04-01
Hüseyin Kurku, İbrahim Solak, Yavuz Turgut Gederet, Mehmet Ali Eryilmaz
Aim: Smoking is accepted as a risk factor for primary chronic diseases such as cardiovascular diseases
and respiratory system diseases and for cancer development. The aim of this study was to indicate the
increase in inflammation in smokers by using high-sensitivity...
Journal of Turkish Clinical Biochemistry
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2021-04-01
Özben Özden Işıklar, Güneş Başol, Burcu Barutçuoğlu, Erkin Bozdemir, Ceyda Kabaroğlu, Zuhal Parıldar, Işıl Mutaf, Dilek Özmen
Objective: After proving that chronic low grade inflammation is an important component of atherosclerotic process, C-reactive protein (CRP) has been started to be used for atherosclerotic vascular disease risk determination together with the other risk factors. In practice, to...
Journal of Turkish Clinical Biochemistry
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2007-04-01
Özgür Aslan, Metin Demir, Ayşenur Atay, Mehmet Hicri Köseoğlu, Mustafa Kaya
Objective: Various inflammatory molecules that are used for diagnosis and monitoring are released
into circulation when a bacterial infection is observed at host organisms. C reactive protein (CRP) is
one of these various molecules, and procalcitonin (PCT) is also an acute...
Journal of Turkish Clinical Biochemistry
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2011-08-01
Emin Savaş Kılavuz, Cihan Kırbaş, Eray Ulu, Nermin Erol
Objective: In this study, we aimed to show whether conditions which cause positive results in 50 gr gestational diabetes screening test also increase the levels of inflammatory markers in pregnant women.
Materials and Methods: Fasting fibrinogen and...
Journal of Turkish Clinical Biochemistry
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2007-12-01
Erkan Söğüt, Enver Avcı, Füsun Üstüner, Erdinç Arıkan
Objective: Various algorithms for predicting coronary atherosclerosis have been established, most of which are based on large epidemiologic and cohort studies. We examined the predictive value of various clinical and biochem ical markers for angiographically defined coronary...
Journal of Turkish Clinical Biochemistry
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2006-04-01
Güler Buğdaycı, Erdinç Serin, Fatih Özcan
Objective: Use of C-Reactive protein in the follow-up of different clinical situations is getting more important. Levels of CRP can be detected by immunonephelometric and immunoturbidimetric methods in the clinical laboratories. The emergency departmentÕs laboratory renders...
Journal of Turkish Clinical Biochemistry
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2007-08-01
Belgin Şenol, Ceyda Kabaroğlu, Saliha Aksun, Sara Habif, Işıl Mutaf, Nevbahar Turgan, Dilek Özmen, Hakan Kültürsay
Purpose: In the recent years, the relationship between inflammation and atherosclerosis induced, which is a chronic inflammatory disease, acute coronary syndromes, including unstable angina and acute myocard infarction, has gained importance. Acute phase reactants, as...
Journal of Turkish Clinical Biochemistry
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2003-12-01
Tuba Hancı, Hakan Türkön, Ayfer Çolak Aydoğdu, Ömür Yıldız, İsmail Karademirci, Işıl Çoker
Objective: Obesity is the leading public health problem in this century. In this study we aimed to evaluate the hsCRP levels which are the indicators of inflammation in obese people (defined with BMI) and assess the relation between obesity and hsCRP.
Materials...
Journal of Turkish Clinical Biochemistry
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2012-04-01
Ayfer Aydoğdu Çolak, Tuba Hancı, Neşe Doğan, Şergır Matlaş, İsmail Karademirci, Füsun Üstüner
Objective: In recent years hsCRP and procalcitonin has started to be used in diagnosis and assessment of the prognosis of cardiovascular diseases. In this study we aimed to evaluate the prognostic significance of alterations in C-reactive protein (CRP) and procalcitonin...
Journal of Turkish Clinical Biochemistry
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2013-12-01
Sibel Bilgili, Gizem Yalçın, Giray Bozkaya, Nuriye Uzuncan, Arife Erdoğan
Purpose: Nitric oxide(NO) is one of the important substances that are synthesized to keep the blood
vessels dilated enough to provide adequate flow and to maintain cerebrovascular homeostasis. Creactive
protein(CRP) is a highly sensitive indicator of inflammation and tissue...
Journal of Turkish Clinical Biochemistry
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2020-12-01
Baysal Karaca, Nuriye Uzuncan, Osman Evliyaoğlu, Ayşe Arısoy, Ayten Coşkuner, Onur Özgenç
Sepsis is defined as systhemic response against infections and frequently caused by gram negative bacteria. It is proposed that the blood levels of acute phase reactants such as Lipopolisaccharide Binding Protein (LBP), C-reactive protein (CRP), mediators of septic cells such as Tumor Necrosis...
Journal of Turkish Clinical Biochemistry
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2003-08-01
Burcu Barutçuoğlu, A. Erkin Bozdemir, Güneş Başol, Zuhal Parıldar, Ceyda Kabaroğlu, M. Işıl Mutaf, Oya Bayındır
Objective: The increase in serum procalcitonin (PCT) levels is a marker of severe systemic inflammation due to bacterial infection and renal excretion plays an important role in its elimination. The aim of this retrospective study is to investigate the relationship between...
Journal of Turkish Clinical Biochemistry
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2008-04-01
Emin Savaş Kılavuz, Nermin Erol
Objective: The aim of this study is to examine the effect of hypeglycemic peak induced by OGTT on
the basal inflammatory state by exploring the serum CRP level diffferencesMaterial and
Methods: I24 patients for suspicous of diabetes who have applied...
Journal of Turkish Clinical Biochemistry
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2009-08-01
Duygu Eryavuz Onmaz, Abdullah Sivrikaya, Sedat Abuşoğlu, Sema Yılmaz, Ali Ünlü
Aim: Rheumatoid arthritis (RA) is an autoimmune disease and its etiology hasnt been fully elucidated.
However, excessive amounts of reactive oxygen derivatives have been detected in the synovial fluids of
patients with RA. Therefore, systemic inflammation and oxidative...
Journal of Turkish Clinical Biochemistry
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2021-12-01
Tugba Arıkan, Mehmet Kelles, Selman Sarıca, Metin Kılınc
Objective: It has been demonstrated that oxidative stress induced tissue damage plays a role in the
pathogenesis of several otolaryngological diseases. The aim of the present study was to evaluate the
selenium (Se), zinc (Zn) and copper (Cu) levels in the plasma of children...
Journal of Turkish Clinical Biochemistry
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2018-12-01
Nergiz Zorbozan, Elif Fırat, Orçun Zorbozan
Aim: This study aims to evaluate repeated tests and unnecessary repeated laboratory tests based on minimum retest intervals.
Materials and Methods: Data regarding thyroid-stimulating hormone (TSH), ferritin, C-reactive protein (CRP), and erythrocyte...
Journal of Turkish Clinical Biochemistry
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2025-12-01
Ayşe Basmakcı, Esra Gürdl, Ayşe Selcen Pala, Orkide Kutlu, Mine Adaş, Mustafa Şahi, Fatih İncirku, Çiğdem Arabacı, Okan Dikker
Aim: We aimed to determine the glypican-3 levels in patients diagnosed with COVID-19, compare these values with the healthy controls, and analyze the evaluation of glypican-3 levels with inflammatory markers, including interleukin-6 (IL-6), to determine its role in disease...
Journal of Turkish Clinical Biochemistry
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2023-04-01
Ünsal Ünüvar, Pınar Akan, Bahri Akdeniz, Önder Kırımlı, Banu Önvural
Objective: The synthesis of matrix metalloproteinase-1 (MMP-1) which is claimed to cause early mortal damage during the first moments of coronary reperfusion, is reported to be induced in-vitro by oxidized low density lipoprotein (LDL). The in- vivo changes in MMP-1, it's...
Journal of Turkish Clinical Biochemistry
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2013-08-01
Rabia Nur Kocabaş, A. Erkin Bozdemir, Güneş Başol, Burcu Barutçuoğlu, Zuhal Parıldar, Ceyda Kabaroğlu, Oya Bayındır
Objective: Cardiovascular diseases (CVD) are the leading causes of death worldwide. After understanding the importance of inflammation in the pathogenesis, CRP usage has been increased for the determination of cardiovascular risk. As an inflammation marker, the relationship...
Journal of Turkish Clinical Biochemistry
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2007-08-01
Veysel Sucu, Müberra Vardar, Ralfi Singer, Mustafa Durmuşcan, Okan Dikker
Objective: Autoimmunity is an important factor in the pathogenesis of Behcet Disease emphasized in
recent years In recent studies, Vitamin D has been demonstrated to play a significant role in immune
system functioning. The measurement of plasma 25-hydroxyvitamin D3levels,...
Journal of Turkish Clinical Biochemistry
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2019-04-01
Celal Kurt, Sembol Yıldırmak, Murat Usta, Ömer Emecen
Aim: The aim of this study is to investigate the possible effects of chronic smoking on serum vitamin D
and some inflammation markers.
Materials and Methods: The smoking history of a total of 110 volunteer adults, 76 females and 34
males, for whom 25...
Journal of Turkish Clinical Biochemistry
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2021-08-01