The official publication of Turkish Clinical Biochemistry Association
Objective: However, the analytical and standardization problems have continued, vitamin D status is usually assessed by measuring the plasma concentration of 25-hydroxyvitamin D [25(OH)D]. The aim of this study was to compared vitamin D levels of 50 healthy volunteers...
Aim: A number of recent reports have investigated the origin of false-positive hCG results. This case report demonstrates a slightly high true positive hCG in a young female patient with chronic kidney disease.
Materials and Methods: The patients serum...
Background: It was calculated total uncertainty of measurement using the repeatability and the uncertainty arising from the commercial quality control and calibrator in the method of immunoassay 25-Hydroxyvitamin D3 and was evaluated the potential impact of its on the...
Aim: Six Sigma methodology used in clinical laboratories is a quality management tool based on statistical calculations, focusing on process variables and providing information about process performance. In this study, we aimed to evaluate the analytical process performances...
Objective: Blood collection tubes with a clot activator are widely used in clinical laboratories. Unexpectedly high results in folate assays obtained on Siemens Advia Centaur XP analyzer triggered a need for an investigation of the effects of blood collection tubes on folate...
Objective: The cardiac troponins are sensitive and specific biochemical markers of myocardial damage. It has been suggested that hemolysis causes interference in the immunometric cardiac troponin assay. The current study aimed to determine the significance of hemolysis as an...
Objective: The accurate and reliable measurement of addictive substances is a very serious problem all over the world because it involves some legal liabilities. This study aims to measure the popular addictive substances using two common techniques and to reveal against...
Aim: Method evaluation studies should be carried out for every new method planned to be used in laboratories. The aim of this study is to determine the analytical performance of the immunoassay method used for determining of plasma 25-hydroxy vitamin D levels and also to...
Aim: Measurement of cardiac troponins is of great importance in the diagnosis and follow-up of acute myocardial infarction. The diagnostic specificity of myocardial infarction has increased with algorithms including serial troponin measurements. It is important that the...
Objectives: Drug abuse tests are applied to determine drug use to combat disease, crime, or substance abuse. We aimed to investigate whether cheaper and more practical plastic tubes can be an alternative to glass tubes for drug abuse analysis in urine.
Material...
Purpose: The purpose of this study is to determine serum B12 and folic acid reference values that can be used in our hospital district population.
Materials and Methods: 300 healthy individuals were chosen according to CLSI Approved Guideline C28-A....
Backgrounds: In the present study, serum levels of turnover markers, β-CTX and N- terminal mid-region osteocalcin were measured to outline their correlation with BMD and their usefulness in diagnosis and follow up of osteoporosis in postmenopausal women.
...Aim: Thyroid hormone tests show circadian rhythm. In this study we investigated the changes of Thyroid Stimulating Hormone (TSH) and free Thyroxine (fT4) test results in apparently healthy individuals and thyroid hormone replacement patients at different times of the...
Objective: To evaluate the consistency between total vitamin B12 and holotranscobalamin (holoTC) measurement results by analyzing holoTC levels in patients with total vitamin B12 deficiency.
Material and Methods: HoloTC level was analyzed by...
Objective: Thyroid function, influenced by age and sex, provides important epidemiological information when evaluated at the population level. This study aimed to investigate age- and sex-related differences in thyroid-stimulating hormone (TSH), free triiodothyronine (fT3),...
Objective: Obesity promotes the development of diseases in many organ systems. The relationship between lipoporotein (a), lipid parameters and insulin resistance which accompany obesity has not been clarified. The correction of dyslipidemia in obesity and insulin resistance is...
Objective: Prostate specific antigen (PSA) and ma ny other tumor markers are suggested to be useful for the biologic activity of the prostate cancer. The aim of our study is to investigate possible relationship between inflammatory markers (high sensitive C-Reactive Protein...
Aim: Cross-reactivity in immunological techniques varies and the frequency depends on the population of the study, technique for detecting the reaction and researchers method. In this study our aim was to evaluate the cross-reactivity in thyroid function tests.
...Objective: The aim of this study is to determine the correlation between insulin resistance and serum IL-8 levels of obese individuals with normal glucose tolerance.
Materials and Methods: 72 obese individuals with the ages ranging from 20 to 59 and...
Objective: Atherosclerotic cardiovascular disease is the leading cause of the increased morbidity and mortality observed in uremic patients. The prevalance of cardiovascular diseases is high in the dialysis patients. Thrombosis is an important contributor to the evolution of...
Aim: In this study, we compared 3 different clot-activator gel tubes to a glass reference tube and evaluated the effect of storage time on 30 different biochemical analytes.
Material and Methods: Blood samples were collected in 4 types of tubes: an...
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