Aim: Leptin is a nonglycolyzed peptide, made of 146amino-acids, that is produced by ob-gene in fat tissue. Leptin in circulation shows its effects by inhibiting Neuropeptide-Y in central nervous system and shows its effects on body fat mass by decreasing appetite and...

Objectives: Protein energy malnutrition and inflammation are among the causes of morbidity in patients with metabolic stress. Because of the adipogenic and somatotrophic effects of insulin, insulin like growth factor-1(IGF-1) and insulin like growth factor binding protein-3...

Objective: Metabolic syndrome is a comorbidity of insulin resistance, impaired glucose tolerance, abdominal obesity, hypertension and dyslipidemia and associated with increased risk of cardiovascular disease. The secretion of adipocytokines such as leptin and adiponectin...

Objective: In this study, we aimed to evaluate the possible effects of leptin and oxidative stress on the pathogenesis of type 1 and type 2 diabetes mellitus.

Material and Methods: Subjects were assigned to four groups: type 1 diabetes group (n=20),...

Objective: The purpose of this stu dy was to investigate the potentially causal relationship between anger management, anxiety and depression with leptin and glycemic control in type 2 diabetic patients.

Methods: Forty Type 2 diabetic patients were...

Our aim was to investigate the role of serum leptin levels in the control of fat mass in Professional athletes. 7 female and 7 male athletes were included in this study. Test subjects have been active in sports life for 2 years. First blood samples were taken at the period when athletes prior...