Objective: In addition to important roles of vitamin D on regulation of bone and mineral metabolism, recent studies have shown that Vitamin D is necessary for many biological actions. The aim of this study was to determine whether Vit D levels have any effects on lipid...

Objective: Subclinical and cli nical hypothyroidism are relatively common endocrine disorders in the general population. Subclinical hypothyroidism is defined as an elevated serum thyroid stimulating hormone (TSH) level associated with normal total or free T4 (fT4) and T3...

Aim: Lipid profile is used to determine the risk of cardiovascular diseases (CVD) and to monitor treatment. Reference change value (RCV) represents the clinical significance of the variation between the results of two consecutive tests and laboratory test results exceeding...

Diabetes mellitus is a metabolic disease characterized by hyperglycemia resulting from defective insulin secretion or resistance to insulin action, or both. Production of sugar alcoholes called as metabolic hypothesis, ischemia-hipoxia oxidative stress, and insufficiency of neurotrophin or...

Objective: The prevalence of coronary artery disease is much higher in men than in women and sex hormones might play a role in these differences via their influence on lipid profile. However, the role of sex hormones in the relationship between male gender and cardiovascular...

Objective: We aimed to determine the relationship between some oxidative and antioxidant parameters and cancer status. Therefore, the activity of serum PON1, an enzyme known as a lipid antioxidant, as well as serum level of TBARS, the end product of lipid peroxidation, and...

Alcohol addiction is one of the leading reasons of liver diseases in many countries. Hepatic steatosis, alcoholic hepatitis, hepatic fibrosis and cirrhosis can be mentioned among the diseases resulting due to alcohol addiction. In recent years, studies have been focused on effect oxidant stress...

Objectives: Protein energy malnutrition and inflammation are among the causes of morbidity in patients with metabolic stress. Because of the adipogenic and somatotrophic effects of insulin, insulin like growth factor-1(IGF-1) and insulin like growth factor binding protein-3...

Objective: The aim of the study was to investigate the relationship between viral load and lipid peroxidation and antioxidant enzymes in patients with hepatitis B virus (HBV) infection.

Materials and Methods: We examined 50 patients (26 male, 24 female)...

Objective: Obesity promotes the development of diseases in many organ systems. The relationship between lipoporotein (a), lipid parameters and insulin resistance which accompany obesity has not been clarified. The correction of dyslipidemia in obesity and insulin resistance is...

Objective: The goal of this study was to investigate the correlation between the ultrasonographic measurements of subcutaneous adipose tissue thickness and serum lipid levels.

Materials and methods: Randomly selected 100 subjects (50 males and 50...

Objective: Sialic acid, known as a risk factor for coronary heart disease is also elevated in serum after myocardial infarction. Because acute myocardial infarction generally develops on the basis of atherosclerotic heart disease, the effect of experimental myocardial...

Background: A sedentary lifestyle is associated with cardiometabolic risk factors and obesity. This study aims to investigate the effects of regular exercise training, acute exercise, and a sedentary lifestyle on levels of miRNA-33, miRNA-335, miRNA-370, miRNA-758, which...

Objective: Stroke, in all over the world, the one of the leading causes of morbidity and mortality especially in the geriatric population. Oxidative stress has an important role in pathophysiology of ischemic stroke. Malondialdehyde (MDA) is an important parameter of...

Objective: In the study, it was aimed to determine the harmony of LDL-C levels determined by enzymatic(direct) and computational method, to have an idea about the optimal request frequency by examining the significance of the percentage changes of repeated LDL-C measurements...

Fatty acid-binding proteins (FABPs) are abundant 14-15-kDa cytoplasmic proteins expressed in almost all mammalian tissues. They coordinate lipid responses in cells and related with metabolic and inflammatory pathways. FABPs bind to hydrophobic ligands, such as saturated and unsaturated long-chain...

Objective: Sperm cryopreservation is the procedure of freezing sperms without loosing their liveliness in various oncological and/or immunological diseases and fertilization problems arousing from the treatments of these diseases. However, a decrease in sperm motiliy, cell...

It has been reported that oxidative stress is increased in diabetes mellitus and the increase in oxidative stress gives rise to complications of this disease. In the present study, we aimed to investigate the effects of vitamin A, E, and C treatments combined with insulin on the oxidative and...

Aim: The present study aimed to determine the reference range values for four lipid parameters associated with chronic diseases that were routinely examined in our laboratory in elderly individuals aged ≥65 years.

Materials and Methods: We determined...

Aim: To investigate the presence of oxidative stress and dyslipidemia, which increase cardiovascular risk, and the effect of gonadotropin replacement therapy on these parameters in patients with Idiopathic Hypogonadotropic Hypogonadism (IHH).

Material and...