The official publication of Turkish Society of Clinical Biochemistry
Purpose: The importance of medical biochemistry laboratories has increased in the ongoing coronavirus disease 2019 (COVID-19) pandemic. This study aimed to reveal the current situation of medical biochemistry specialists and medical biochemistry laboratories in 1 year from...
Aim: With the COVID-19 pandemic, clinicians' expectations from laboratory professionals and the desired test volumes have increased significantly. The specialist physicians do not sufficiently understand the laboratory team's workflow struggling with the pandemic at the...
Objective: This study aimed to evaluate the frequency of repeat lipoprotein(a) testing, determine whether repeated measurements changed risk classification, assess the clinical significance of observed changes using the reference change value, and investigate whether the...
Objective: Hemoglobinopathies are an array of disorders that affect hemoglobin (Hb) function. HPLC is by far the most common technique used for detection of hemoglobinopathies worldwide. The aim of this study is to evaluate 3-year retrospective data of a tertiary hospital in...
Objective: Automated hematology analyzer flags may provide early warning signals for hematological malignancies. This study aimed to evaluate the diagnostic performance of Sysmex XN-1000 analyzer flags and to develop a multivariable prediction model for identifying active...
Introduction: The disease caused by SARS-CoV-2, which the World Health Organization has considered as a pandemic, was named COVID-19 and has since spread worldwide. The COVID-19 pandemic has drastically changed the way we live and work. During events like COVID-19, it is...
Aim: It was aimed to determine predictive markers for the need for intensive care unit (ICU) hospitalization in patients with coronavirus infection.
Material and Methods: This study was performed retrospectively from data of patients hospitalized with...
Aim: In this study, we compared 3 different clot-activator gel tubes to a glass reference tube and evaluated the effect of storage time on 30 different biochemical analytes.
Material and Methods: Blood samples were collected in 4 types of tubes: an...
Aim: High-risk laboratory results, known as Critical or panic laboratory value, is an indicator of a lifethreatening condition. The test results of critical laboratory value levels that are not determined and communicated by clinicians prevent early diagnosis and treatment,...
Aim: The COVID outbreak is a serious health problem affecting socio-economic life and healthcare systems worldwide. Although the role of Semaphorins in some diseases is relatively known, the association of these molecules with the pathogenesis of COVID-19 remains unclear....
Aim: Early risk classification after acute myocardial infarction is very important for the prediction of complications. In this study, it was aimed to find the most sensitive panel in the prediction of prognosis after acute myocardial infarction by multi-biomarker...
Aim: Homocitrulline (Hcit) is a modified amino acid originated by carbamylation of lysine residues and it is considered a potential biomarker in inflammatory diseases. Behçet's disease (BD) is an autoinflammatory disease, the diagnosis of the disease is based on clinical...
Aim: Quality improvement studies in clinical laboratories play a vital role in achieving accurate and reliable patient results. Measurement uncertainty is important for the quality and reliability of test results. Since laboratory results inherently involve uncertainty, ISO...
Aim: The aim of this study was (1) to compare the serum insulin, ghrelin, obestatin and, copeptin levels between pregnant and non-pregnant women and (2) investigate the changes in these parameters in pregnant women that measured at before and second hour after 75 gram (g)...
Aim: Many mediators and biomarkers play a role in the pathogenesis of bacterial sepsis (BS) which is still not fully illimunated.The aim was to analyze intracellular oxidised glutathione (GSSG)/reduced glutathione (GSH) and serum thiol/disulfide (extracellular) homeostasis...
Aim: Six sigma is a quality management tool used to evaluate analytical process performance. We evaluated the performance of biochemical and immunological tests on a Roche Cobas 8000 device in our laboratory using sigma metrics.
Materials and Methods:...
Aim: Lipid profile is used to determine the risk of cardiovascular diseases (CVD) and to monitor treatment. Reference change value (RCV) represents the clinical significance of the variation between the results of two consecutive tests and laboratory test results exceeding...
Aim: Pancreatic cancer (PC) is a disease with complex and poorly understood etiology. One of the common risk factors of PC is diabetes mellitus (DM). Increased carbohydrate antigen (CA) 19-9 levels can be used as a biomarker in diagnosis of PC. However, CA 19-9 levels have...
Aim: Many mediators and biomarkers play a role in the pathogenesis of bacterial sepsis (BS) which is still not fully illimunated. The aim was to analyze intracellular oxidised glutathione (GSSG)/reduced glutathione (GSH) and serum thiol/disulfide (extracellular) homeostasis...
Objective: It has been demonstrated that oxidative stress induced tissue damage plays a role in the pathogenesis of several otolaryngological diseases. The aim of the present study was to evaluate the selenium (Se), zinc (Zn) and copper (Cu) levels in the plasma of children...
Objective: The goal of this study was to investigate the correlation between the ultrasonographic measurements of subcutaneous adipose tissue thickness and serum lipid levels.
Materials and methods: Randomly selected 100 subjects (50 males and 50...
Objective: Obesity represents a significant global health concern characterized by substantial metabolic abnormalities and a heightened risk of developing type 2 diabetes mellitus (T2DM). Novel peptides including irisin, adropin, and preptin have been shown to play important...
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Method validation, analyzer comparisons, reference intervals, quality indicators, preanalytical studies, and instructive clinical case reports.
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