Sükriye Miray Kilincer Bozgul, Merve Doğru Efgan, Zehra Tuba Karaman, Rabia Yelli, Hande Dik Avcı, Güneş Ak, Ajda Güneş, Caner Acar, İlkçe Akgün Kurtulmuş, Devrim Bozkurt
Aim: In the present study, we aimed to evaluate the association between disseminated intravascular coagulation (DIC) score and mortality among adult sepsis patients in intensive care unit (ICU).
Material and Methods: In this retrospective cohort study,...
Journal of Turkish Clinical Biochemistry
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2024-08-01
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DOI: 10.56615/tkbd.2024.08
Evin Kocatürk, Alparslan Birdane, Arif Alper Cevik, Ertugrul Colak, Ahmet Musmul, Omer Colak
Aim: Early risk classification after acute myocardial infarction is very important for the prediction of
complications. In this study, it was aimed to find the most sensitive panel in the prediction of prognosis
after acute myocardial infarction by multi-biomarker...
Journal of Turkish Clinical Biochemistry
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2022-12-01
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DOI: 10.56615/tkbd.2022.14
Bilge Karatoy Erdem, Halide Akbas
Patients with chronic kidney disease (CKD) have a high risk of cardiovascular morbidity and mortality.
Vascular calcification (VC) is the most important cause of cardiovascular morbidity and mortality both in
the general population and CKD. VC is mainly associated with mineral metabolism and...
Journal of Turkish Clinical Biochemistry
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2017-08-01
Rasime Derya Güleç, Fatma Demet Arslan, Taner Çalışkan, Nimet Şenoğlu, Nisel Yılmaz
Objectives: Identifying COVID-19 patients with risk of adverse outcomes at first admission to the
intensive care unit has several diagnostic challenges. The concentration of acute phase proteins
synthesized by the liver increases or decreases markedly in the serum following...
Journal of Turkish Clinical Biochemistry
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2022-04-01
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DOI: 10.56615/tkbd.2022.05
Bayram Şen, Oğuzhan Okcu, Medeni Arpa, Remzi Adnan Akdoğan
Aim: Colon cancer, accounting for almost 10% of all cancers in both genders worldwide, is the fourth most common cause of cancer-related deaths. Approximately 95% of cases are originated from adenomas. In recent years, early detection of colon-borne pathologies and...
Journal of Turkish Clinical Biochemistry
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2023-12-01
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DOI: 10.56615/tkbd.2023.19
Ali Volkan Özdemir, Arzu Akağaç Etem, Soycan Mızrak
Background: The purpose of this study was to investigate the superiority of serum cystatin C levels
over serum urea and creatinine in evaluating kidney functions in intensive care unit patients.
Material and Methods: 65 patients in intensive care unit...
Journal of Turkish Clinical Biochemistry
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2015-08-01
Sibel Bilgili, Özlem Uğurlu, Giray Bozkaya, Nuriye Uzuncan, Baha Zengel
Aim: Chronic kidney disease (CKD) is highly prevalent, with increasing numbers of patients affected by
the disease world-wide (1). Anemia is a common complica- tion that contributes to the burden of
disease associated with CK D, and it impacts negatively on cardiovascular...
Journal of Turkish Clinical Biochemistry
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2019-12-01
Seda V. İrer, Gülinnaz Alper
In research studies performed to enlighten the diagnosis and pathogenesis of various diseases and to investigate possible treatment strategies, experimental animal models provide many advantages to the investigators. Diabetes Mellitus is a chronic metabolic disease which lasts for whole life,...
Journal of Turkish Clinical Biochemistry
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2004-12-01
Emel Altekin, Ahmet Solak, Pınar Tuncel
Screening for fecal occult blood has been shown to be effective in reducing the colorectal cancer mortality. Guaiac-based tests are one of the most frequently used screening tests, but their false positivity and negativity rates are quite high. Peroxidase enzyme, found in many fruits and...
Journal of Turkish Clinical Biochemistry
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2003-12-01
Selda Demirtaş, Gökhan Nergizoğlu, Levent Karaca
In chronic renal failure, high plasma homocysteine levels are a common finding and in uremia almost the rule. The cause of hyperhomocysteinemia in ESRD (end stage renal disease) whether it lies in an impared renal or extrarenal metabolism or through uremic retention toxins, is still under...
Journal of Turkish Clinical Biochemistry
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2003-04-01
Fatma Şen, Rumeysa Çiftçi, Hacı Kemal Erdemli, Ramazan Kocabaş, Leyla Kılıç, İbrahim Yıldız, Hamza Uğur Bozbey, Ethem Zobacı, Musa Zorlu
Objective: Hyponatremia may be asymptomatic and sometimes may increase the mortality rates of
many diseases by resulting in neurological impairement. In patients with malignancies, hyponatremia
may occur due to cancer itself or due to treatment of cancer. In this study, we...
Journal of Turkish Clinical Biochemistry
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2014-04-01
Mehmet Gürbilek, Çiğdem Damla Deniz, Mehmet Sinan İyisoy, Gamze Demirel, Nahide Baran, Mehmet Özcan
Objective: Since the emergence of Coronavirus Disease 2019 (Covid-19) in December 2019, it has
turned into a pandemic. Covid-19 infection; can trigger pulmonary inflammation and also cause acute
lung injury. In cases with severe pneumonia, long hospital stays and high...
Journal of Turkish Clinical Biochemistry
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2022-04-01
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DOI: 10.56615/tkbd.2022.06
Aynur Kırbaş, Serkan Kırbaş, Ömer Anlar, Hasan Efe, Adnan Yılmaz
Objective: Stroke, in all over the world, the one of the leading causes of morbidity and mortality
especially in the geriatric population. Oxidative stress has an important role in pathophysiology of
ischemic stroke. Malondialdehyde (MDA) is an important parameter of...
Journal of Turkish Clinical Biochemistry
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2011-08-01
Hüseyin Özyurt, Şemsettin Şahin, Aziz Fikret Özuğurlu, Ömer Atış, İsmail Benli, Leyla Aydoğan, Beytullah Yıldırım, Resul Yılmaz
Objective: Coeliac disease is an autoimmune enteropathy constituted by the immun system and in
genetically susceptible patients it is triggered by the consumption of gluten containing wheat, barley and rye made foods. Coeliac d isease is the only lifelong food allergy....
Journal of Turkish Clinical Biochemistry
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2009-12-01
Arzu Ateş, Ayça Tuzcu, Aslıhan Büyüköztürk
Purpose: Although most studies showed that the increase of cardiac biomarkers due to myocardial injury during coronavirus disease (COVID-19) is a strong predictor of adverse clinical events, few studies compared other causes of myocardial injury and COVID-19. In our study,...
Journal of Turkish Clinical Biochemistry
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2025-08-01
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DOI: 10.56615/tkbd.2025.06
Feray Binbaş, Nuriye Uzuncan, Dilek Aslanca, Kutlay Naci Tutucu, Kadriye Akıllı, Baysal Karaca
Objective: Atherosclerotic cardiovascular disease is the leading cause of the increased morbidity and mortality observed in uremic patients. The prevalance of cardiovascular diseases is high in the dialysis patients. Thrombosis is an important contributor to the evolution of...
Journal of Turkish Clinical Biochemistry
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2005-08-01
Işıl Çakır, Nahide Ekici Günay, Ahmet Oğuz Baktır
Objective: ST-segment elevation myocardial infarction (STEMI) is an important cause of morbidity and
mortality. Platelet (PLT) activation and thrombosis have important roles in the process of atherosclerosis
that is one of the most important cause of acute ischaemic...
Journal of Turkish Clinical Biochemistry
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2019-12-01