Aim: To evaluate the relationship between serum oxidant-antioxidant levels and the duration of the illness, disease activity and treatment modality in patients with axial spondyloarthritis (axSpA).

Material and Methods: Fourty two patients with axSpA...

Objective(s):Unexplained infertility (UI) is a multifaceted reproductive disorder with an ambiguous cause. Oxidative stress has arisen as a possible factor in its pathophysiology. This study sought to evaluate the significance of the equilibrium between oxidative and antioxidant levels, alongside...

Purpose: To investigate the effects of melatonin on serum paraoxonase and lactonase activities in isoproterenol-induced myocardial infarction.

Materials and Methods: Rats were divided into four groups as control, melatonin, ISO and ISO+melatonin....

Dietary cholesterol is suggested to cause atherosclerosis and to increase the production of free radicals. It is reported that hypercholesterolemic diet may make some changes on the antioxidant system. In our study, we aimed to observe the effect of N-acetylcysteine (NAC) treatment on the...

Objective: Stroke, in all over the world, the one of the leading causes of morbidity and mortality especially in the geriatric population. Oxidative stress has an important role in pathophysiology of ischemic stroke. Malondialdehyde (MDA) is an important parameter of...

Aim: During iron deficiency anemia (IDA), increased oxidative stress is accompanied by reduction in antioxidant defense systems and increased lipid peroxidation. We aimed to assess oxidative balance and Deoxyribonucleic Acid (DNA) damage in reproductive-aged women with...

Diabetes mellitus is a metabolic disease characterized by hyperglycemia resulting from defective insulin secretion or resistance to insulin action, or both. Production of sugar alcoholes called as metabolic hypothesis, ischemia-hipoxia oxidative stress, and insufficiency of neurotrophin or...

Objective: We aimed to determine the relationship between some oxidative and antioxidant parameters and cancer status. Therefore, the activity of serum PON1, an enzyme known as a lipid antioxidant, as well as serum level of TBARS, the end product of lipid peroxidation, and...

Endometriosis is frequently associated with infertility and spontaneous abortus. Studies which had been carried on the subjects with endometriosis revealed the abnormal expression of the antioxidant defense enzymes, and suggested an inbalance in free radical metabolism. This study was designed to...

Purpose: Obstructive jaundice leads to hepatic injury and fibrosis. Icterus causes immunologic depression resulting in bacterial translocation. In this study, we aimed to investigate the effects of vitamin E and L-arginine supplementation on glutathione systems and bacterial...

Biological thiols are one of the most important anti-oxidant defense mechanism in protecting cells against oxidative stress. Their determination in biological materials is carried out mainly by different spectrophotometric assays. In this study; one of the commonly used spectrophotometric assay...

Aim: The oxidative stress which is caused by free radicals can play role in emerging and/or progressing many diseases. Hyperthyroidism can induce a lot of changes dealing with the systems of nitric oxide (NO) and antioxidant systems of several tissues in increasing the...

Alcohol addiction is one of the leading reasons of liver diseases in many countries. Hepatic steatosis, alcoholic hepatitis, hepatic fibrosis and cirrhosis can be mentioned among the diseases resulting due to alcohol addiction. In recent years, studies have been focused on effect oxidant stress...

Objective: Nicotine is an important component of cigarette smoke. Nicotine administration may result in oxidative stress by inducing the generation of reactive oxygen species in the periphery and central nervous system. Numerous epidemiological studies have demonstrated an...