The official publication of Turkish Society of Clinical Biochemistry
Purpose: Activation of the renin-angiotensin system leads to an increase in oxidative stress. We investigated erythrocyte antioxidant enzymes, glutathione peroxidase, glutathione reductase and glutathione-S-transferase activities and as an index for oxidative stress plasma...
Aim: To investigate the presence of oxidative stress and dyslipidemia, which increase cardiovascular risk, and the effect of gonadotropin replacement therapy on these parameters in patients with Idiopathic Hypogonadotropic Hypogonadism (IHH).
Material and...
Aim: During iron deficiency anemia (IDA), increased oxidative stress is accompanied by reduction in antioxidant defense systems and increased lipid peroxidation. We aimed to assess oxidative balance and Deoxyribonucleic Acid (DNA) damage in reproductive-aged women with...
Objective: Stroke, in all over the world, the one of the leading causes of morbidity and mortality especially in the geriatric population. Oxidative stress has an important role in pathophysiology of ischemic stroke. Malondialdehyde (MDA) is an important parameter of...
Aim: Many mediators and biomarkers play a role in the pathogenesis of bacterial sepsis (BS) which is still not fully illimunated.The aim was to analyze intracellular oxidised glutathione (GSSG)/reduced glutathione (GSH) and serum thiol/disulfide (extracellular) homeostasis...
Aim: Many mediators and biomarkers play a role in the pathogenesis of bacterial sepsis (BS) which is still not fully illimunated. The aim was to analyze intracellular oxidised glutathione (GSSG)/reduced glutathione (GSH) and serum thiol/disulfide (extracellular) homeostasis...
Aim: Rheumatoid arthritis (RA) is an autoimmune disease and its etiology hasnt been fully elucidated. However, excessive amounts of reactive oxygen derivatives have been detected in the synovial fluids of patients with RA. Therefore, systemic inflammation and oxidative...
Purpose: To investigate the effects of melatonin on serum paraoxonase and lactonase activities in isoproterenol-induced myocardial infarction.
Materials and Methods: Rats were divided into four groups as control, melatonin, ISO and ISO+melatonin....
Aim: In this study, it was aimed to examine the relationship between serum levels of neopterin, which is considered a marker of cellular immunity and oxidative stress, and the presence of H. pylori, which causes both inflammation and increased oxidative stress.
...Aim: Physical, sexual, biological, psychological and social changes occur in the adolescent period. Vitamin D is an anti-inflammatory hormone that regulates the body's calcium (Ca) and phosphorus (P) balance, provides bone development, contributes to the formation of the...
Objective: In this study, we aimed to evaluate the possible effects of leptin and oxidative stress on the pathogenesis of type 1 and type 2 diabetes mellitus.
Material and Methods: Subjects were assigned to four groups: type 1 diabetes group (n=20),...
Aim: During pregnancy, metabolic and oxidative changes are seen, including various trace elements and oxidative stress. The main purpose of this study was to evaluate zinc, copper concentrations and oxidative status compared to trimesters in normal pregnancy.
...Aim: Chronic kidney disease (CKD) is highly prevalent, with increasing numbers of patients affected by the disease world-wide (1). Anemia is a common complica- tion that contributes to the burden of disease associated with CK D, and it impacts negatively on cardiovascular...
Aim: The aim was to determine if the malondialdehyde (MDA) and advanced oxidation products of protein (AOPPs) levels, which are oxidative stress parameters, can be used to determine the degree of coronary artery disease.
Materials and Methods: The...
Objective: Colorectal cancer is one of the most endemic cancers causing significant health problems which decreases life quality and causes job loss. As in several cancer types, it is assumed that oxidative damage and consequent inşammation may have an effect on colorectal...
Aim: To evaluate the relationship between serum oxidant-antioxidant levels and the duration of the illness, disease activity and treatment modality in patients with axial spondyloarthritis (axSpA).
Material and Methods: Fourty two patients with axSpA...
Purpose: Portal hypertension (PHT) is a common clinical syndrome, characterized by a pathological increase in portal pressure and hemodynamic changes. It is known that the oxidative stress is a mediator in the pathogenesis of PHT. Beta-blockers (propranolol), somatostatin and...
Objective: The oxidative stress and renal vasoconstriction are considered to have an effect on the pathophysiology of contrast induced nephropathy. In this study, we aimed to evaluate the effects of contrast agents on serum creatinine, total antioxidant capacity and estimated...
Objective: We aimed to determine the relationship between some oxidative and antioxidant parameters and cancer status. Therefore, the activity of serum PON1, an enzyme known as a lipid antioxidant, as well as serum level of TBARS, the end product of lipid peroxidation, and...
Objective: The aim of this study is to investigate whether there is any protective effect of a regular endurance exercise on the L-Thyroxine-induced oxidative stress in lung tissue of rats.
Materials and methods: Twenty-three male Sprague Dawley rats...
Objective: It has been demonstrated that oxidative stress induced tissue damage plays a role in the pathogenesis of several otolaryngological diseases. The aim of the present study was to evaluate the selenium (Se), zinc (Zn) and copper (Cu) levels in the plasma of children...
Fully Diamond OA with no APCs and no submission fees. Your research is freely available to readers worldwide from the day it publishes.
Double-blind peer review from an active editorial team returns a first decision in about 30 days, keeping your manuscript moving.
Backed by the Turkish Society of Clinical Biochemistry, JTCB welcomes submissions from researchers worldwide and reaches an international laboratory audience.
Method validation, analyzer comparisons, reference intervals, quality indicators, preanalytical studies, and instructive clinical case reports.
All manuscripts publish in English and follow ICMJE and COPE guidelines, with Crossref DOIs and TR Dizin indexing ensuring global discoverability.