Purpose: To assess the role of NMP22 and cytology in diagnosing primary and recurrent bladder cancer and to compare the sensitivity, specificity, positive and negative predictive values, accuracy by means of staging, grading, dimensions and the number of the tumours.

Aim: Although, urine culture requests to diagnose urinary tract infection (UTI) are very common, about 70-80% of urine samples received in the laboratory are found to be negative. This means increased laboratory workload and cost. Urinary leukocyte esterase and nitrite are...

Aim: Prostate cancer is the second major cause of cancer-related deaths in men. Digital rectal examination, serum PSA and biopsy are the main tools used in the diagnosis of prostate cancer. The low specificity of PSA leads to unnecessary biopsies. Therefore, biomarkers with...

Purpose: The correct analysis of types and amounts of amino acids is highly important in the diagnosis of inborn errors of metabolism. The results obtained from heel blood drop and plasma of patients who were referred from primary health care institutions with pre-diagnosis...

Objective: Automated hematology analyzer flags may provide early warning signals for hematological malignancies. This study aimed to evaluate the diagnostic performance of Sysmex XN-1000 analyzer flags and to develop a multivariable prediction model for identifying active...

Aim: /b> In this study, we evaluated the analytical performance and diagnostic adequacy of the activity and mass methods used for the measurement of CK-MB, a laboratory marker for the diagnosis of acute myocardial infarction (AMI). In addition, the differences between CK-MB...

Objective: Urine culture test (UCT), which is the gold-standard for urinary tract infections (UTI), requires higher cost, labour and time than complete urinalysis (CU). Therefore, it is important to assess prediction performance of CU's for UCT. The aim of our study is to...

Objective: Troponin I is a reliable and sensitive marker which is used to evaluate the myocardial injury. However there are different cut-off values for Troponin I due to different measurement technics. Therefore it is recommended that laboratories must define their own...

Aim: During iron deficiency anemia (IDA), increased oxidative stress is accompanied by reduction in antioxidant defense systems and increased lipid peroxidation. We aimed to assess oxidative balance and Deoxyribonucleic Acid (DNA) damage in reproductive-aged women with...

Aim: Colon cancer, accounting for almost 10% of all cancers in both genders worldwide, is the fourth most common cause of cancer-related deaths. Approximately 95% of cases are originated from adenomas. In recent years, early detection of colon-borne pathologies and...

Objective: The presence of malignant pleural effusion in lung cancer refers to an advanced stage and the survive of these patients after surgical resection is unfortunately poor. The nature of pleural effusion should be clarified in lung cancer as it is important for accurate...

Objective: Iron Deficiency Anemia (IDA) and Beta Thalassemia Minor (BTM) are the most common causes of microcytic hypochromic anemia. In the last four decades many formulas have been proposed to discriminate between two common causes of microcytic hypochromic anemia. An...

Objective: Gestational diabetes mellitus is one of the most frequent complications in pregnancy which may create a health risk for the mother and the child. Different criteria may be used in the diagnosis of gestational diabetes mellitus. In the present study we aimed to test...

Objective: IUrinary tract infection (UTI) is a common disease in children. Rapid and reliable diagnosis of UTI is mandatory for the prevention of complications. The aim of the present study was to assess whether or not automated urine analysis can be used as a rapid diagnostic...